GENE：LTBP2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | LTBP2 |
| FullNmae | latent transforming growth factor beta binding protein 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:6715 |
| EnsembleID | ENSG00000119681 |
| Uniprot | Q14767 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| LTBP2 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| LTBP2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| LTBP2 | GO:0005201,GO:0005509,GO:0005515,GO:0005576,GO:0005615,GO:0006605,GO:0007179,GO:0008201,GO:0009306,GO:0019838,GO:0031012,GO:0050436,GO:0062023,GO:0070062,GO:0097435,GO:0097435 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | LTBP2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | LTBP2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | LTBP2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | LTBP2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | LTBP2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | LTBP2 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | LTBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | LTBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | LTBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | LTBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | LTBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | LTBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | LTBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | LTBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | LTBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | LTBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | LTBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | LTBP2 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002C83DA | LTBP2 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237E04 | LTBP2 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000122F23 | LTBP2 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AA845 | LTBP2 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001481F9 | LTBP2 | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AB0E | LTBP2 | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ACA7C | LTBP2 | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003B59DF | LTBP2 | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BA274 | LTBP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004B4B85 | LTBP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FD1A | LTBP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E226A | LTBP2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008B558 | LTBP2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SDC4 | LTBP2 | 25348397 | N/A | enzyme linked immunosorbent assay | ComPPI |
| FYN | LTBP2 | 17474147 24234451 25348397 | physical association | peptide array | ComPPI,IntAct |
| HSPG2 | LTBP2 | 25348397 | N/A | enzyme linked immunosorbent assay | ComPPI |
| LTBP2 | ABL1 | 17474147 24234451 25348397 | physical association | peptide array | ComPPI,IntAct |
| LTBP2 | FBN1 | 19681046 27898060 | stimulant | N/A | OmniPath |