Gene Information gene info

GENE:PA2G4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PA2G4
FullNmae proliferation-associated 2G4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8550
EnsembleID ENSG00000170515
Uniprot Q9UQ80

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PA2G4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PA2G4 GO:0003676,GO:0003714,GO:0003723,GO:0005515,GO:0005576,GO:0005634,GO:0005730,GO:0005737,GO:0006364,GO:0006417,GO:0016020,GO:0031625,GO:0035578,GO:0043066,GO:0045597,GO:0045892,GO:0070062,GO:1990904

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PA2G4 NPM1 17951246 23180781 physical association anti tag coimmunoprecipitation InnateDB
PA2G4 E2F1 21085677 23180781 physical association anti tag coimmunoprecipitation InnateDB
PA2G4 E2F3 21085677 23180781 physical association anti tag coimmunoprecipitation InnateDB
E2F4 PA2G4 21085677 23180781 physical association anti tag coimmunoprecipitation InnateDB
E2F5 PA2G4 21085677 23180781 physical association anti tag coimmunoprecipitation InnateDB
RB1 PA2G4 21085677 23180781 physical association anti tag coimmunoprecipitation InnateDB
PA2G4 RBL1 21085677 23180781 physical association anti tag coimmunoprecipitation InnateDB
RBL2 PA2G4 21085677 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PA2G4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PA2G4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PA2G4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PA2G4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PA2G4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PA2G4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PA2G4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PA2G4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYB PA2G4 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYC PA2G4 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A PA2G4 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001EFBE3 PA2G4 19944095 rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr miRSponge
URS00001EFBE3 PA2G4 19944095 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr TarBase
URS00000EC1BE PA2G4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 PA2G4 23622248 25416803 25926693 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clash,miRNA interference luciferase reporter assay TarBase
URS00003D5391 PA2G4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 PA2G4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE PA2G4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D PA2G4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000148B91 PA2G4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 PA2G4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 PA2G4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002AB575 PA2G4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 PA2G4 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKCD PA2G4 22135298 phosphorylation N/A PhosphoSite
PAK1 PA2G4 22135298 phosphorylation N/A PhosphoSite
PRKCA PA2G4 22135298 phosphorylation N/A PhosphoSite
PA2G4 RPL4 25361965 interaction type N/A PTMCode2
RPL4 PA2G4 25361965 interaction type N/A PTMCode2
PA2G4 NCL 25361965 interaction type N/A PTMCode2
NCL PA2G4 25361965 interaction type N/A PTMCode2
PA2G4 AR 25361965 interaction type N/A PTMCode2
AR PA2G4 25361965 interaction type N/A PTMCode2
PA2G4 RNF20 25361965 interaction type N/A PTMCode2
RNF20 PA2G4 25361965 interaction type N/A PTMCode2
ERBB3 PA2G4 25361965 interaction type N/A PTMCode2
PA2G4 ERBB3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SF3A3 PA2G4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HNRNPK PA2G4 25348397 N/A physical interaction ComPPI
EXOSC5 PA2G4 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SNRPB2 PA2G4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2I PA2G4 25348397 N/A physical interaction ComPPI
CBSL PA2G4 25348397 N/A physical interaction ComPPI
DDX21 PA2G4 25348397 N/A physical interaction ComPPI
ATP5F1B PA2G4 25348397 N/A physical interaction ComPPI
NPM1 PA2G4 15064750 24234451 25348397 26496610 colocalization,association anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
VIM PA2G4 25348397 N/A physical interaction ComPPI
UBL4A PA2G4 25348397 N/A physical interaction ComPPI
TRAF6 PA2G4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RPL11 PA2G4 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FOXB1 PA2G4 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ACTB PA2G4 25348397 N/A physical interaction ComPPI
PTPN6 PA2G4 25348397 N/A physical interaction ComPPI
KEAP1 PA2G4 25348397 N/A physical interaction ComPPI
MCM2 PA2G4 25348397 N/A physical interaction ComPPI
RPL10 PA2G4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKCA PA2G4 11325528 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
FBXW7 PA2G4 25348397 N/A physical interaction ComPPI
SND1 PA2G4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ATR PA2G4 25348397 N/A physical interaction ComPPI
JUN PA2G4 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RB1 PA2G4 11268000 14525934 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
AR PA2G4 14525934 15583694 24234451 25348397 9565586 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HMGA1 PA2G4 25348397 N/A filter binding,physical interaction ComPPI
DHX9 PA2G4 25348397 N/A physical interaction ComPPI
NELFB PA2G4 25348397 N/A physical interaction ComPPI
RPL18A PA2G4 25348397 N/A physical interaction ComPPI
LIG4 PA2G4 25348397 N/A physical interaction ComPPI
EIF5B PA2G4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PKN1 PA2G4 25348397 N/A physical interaction ComPPI
U2AF2 PA2G4 25348397 N/A physical interaction ComPPI
PDIA3 PA2G4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NRBF2 PA2G4 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDKN2A PA2G4 25348397 N/A physical interaction ComPPI
PRKAA1 PA2G4 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2N PA2G4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NTRK1 PA2G4 25348397 N/A physical interaction ComPPI
IDH2 PA2G4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
YBX1 PA2G4 25348397 N/A physical interaction ComPPI
PDPK1 PA2G4 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
E2F1 PA2G4 11268000 24234451 25348397 physical association pull down ComPPI,IntAct
HSPA1A PA2G4 25348397 N/A physical interaction ComPPI
HSPA1B PA2G4 25348397 N/A physical interaction ComPPI
SIN3A PA2G4 14525934 16254079 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PRKCB PA2G4 11325528 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MAP2 PA2G4 25348397 N/A physical interaction ComPPI
RPL28 PA2G4 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 PRKCG 11325528 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PA2G4 HDAC2 12682367 24234451 25348397 27898060 physical association two hybrid,physical interaction,in vitro ComPPI,IntAct,OmniPath
PA2G4 SUMO4 14525934 16236267 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PA2G4 LOX 24234451 25118846 25348397 physical association two hybrid ComPPI,IntAct
PA2G4 SGK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 ERBB3 10682683 11325528 14525934 15583694 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,IntAct
PA2G4 MTOR 25348397 N/A physical interaction ComPPI
PA2G4 USP39 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 ATG101 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 NIPSNAP2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 PIK3C2A 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 PRKAG1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 SH3GLB2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 IKBKG 25348397 N/A physical interaction ComPPI
PA2G4 MDM2 25348397 N/A physical interaction ComPPI
PA2G4 AKT1 25348397 N/A physical interaction ComPPI
PA2G4 HDAC5 25348397 N/A physical interaction ComPPI
PA2G4 TERF1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
PA2G4 CDK2 25348397 N/A physical interaction ComPPI
PA2G4 FUS 25348397 N/A physical interaction ComPPI
PA2G4 ATP6V0A1 25348397 N/A physical interaction ComPPI
PA2G4 SERBP1 25348397 N/A physical interaction ComPPI
PA2G4 EIF2A 25348397 N/A physical interaction ComPPI
PA2G4 NCL 15064750 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PA2G4 TOP1 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 IGF2BP2 25348397 N/A physical interaction ComPPI
PA2G4 RPLP0 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 RPLP0P6 25348397 N/A physical interaction ComPPI
PA2G4 H1-1 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 RPL4 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 RPL8 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 RPL15 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 RPL18 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 RPL21 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 RPL12 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 RPL27 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 RPL30 25348397 N/A physical interaction ComPPI
PA2G4 RPLP2 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 EEF2K 25348397 N/A physical interaction ComPPI
PA2G4 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PA2G4 ITGA4 25348397 N/A physical interaction ComPPI
PA2G4 HMGA2 25348397 N/A physical interaction ComPPI
PA2G4 DIMT1 25348397 N/A physical interaction ComPPI
PA2G4 EIF3K 25348397 N/A physical interaction ComPPI
PA2G4 NMT1 25348397 N/A physical interaction ComPPI
PA2G4 FAU 25348397 N/A physical interaction ComPPI
PA2G4 FAU 25348397 N/A physical interaction ComPPI
PA2G4 G3BP1 25348397 N/A physical interaction ComPPI
PA2G4 IGF2BP3 25348397 N/A physical interaction ComPPI
PA2G4 KRT17 25348397 N/A physical interaction ComPPI
PA2G4 RPS27L 25348397 N/A physical interaction ComPPI
PA2G4 RPL23A 25348397 N/A physical interaction ComPPI
PA2G4 HSPA4 25348397 N/A physical interaction ComPPI
PA2G4 STUB1 25348397 N/A physical interaction ComPPI
PA2G4 LAMB1 25348397 N/A physical interaction ComPPI
PA2G4 HNRNPA2B1 25348397 N/A physical interaction ComPPI
PA2G4 MOV10 25348397 N/A physical interaction ComPPI
PA2G4 CUL7 25348397 N/A physical interaction ComPPI
PA2G4 OBSL1 25348397 N/A physical interaction ComPPI
PA2G4 CCDC8 25348397 N/A physical interaction ComPPI
PA2G4 CDKN2A 25348397 N/A physical interaction ComPPI
PA2G4 ESR1 25348397 N/A physical interaction ComPPI
PA2G4 TMED7 25348397 N/A physical interaction ComPPI
PA2G4 MYCBP 25348397 N/A physical interaction ComPPI
PA2G4 OFD1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 SPICE1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PA2G4 FOXH1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PA2G4 FOXI2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PA2G4 FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PA2G4 EIF2S2 25348397 N/A physical interaction ComPPI
PA2G4 PTP4A1 25348397 N/A physical interaction ComPPI
PA2G4 ANXA5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 TRAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 NANS 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 PLS3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 MRPL12 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 SLC25A10 25348397 N/A physical interaction ComPPI
PA2G4 CRNN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 ZNF207 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 CPNE3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 CS 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 PYGL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 DNAJC8 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 CPSF6 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 PPA1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 SF3A1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 ECHS1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 SRP68 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 MYL12B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 AIMP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 CBS 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PA2G4 BRCA1 25348397 N/A physical interaction ComPPI
PA2G4 YAP1 25348397 N/A physical interaction ComPPI
PA2G4 PABPN1 15064750 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PA2G4 RPL24 15064750 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PA2G4 ATG5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PA2G4 EIF6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PA2G4 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PA2G4 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PA2G4 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PA2G4 ACADVL 18337751 24234451 25348397 association biochemical ComPPI,IntAct
PA2G4 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
PA2G4 PPTC7 24234451 25348397 28330616 association pull down ComPPI,IntAct
PA2G4 PHOSPHO1 24234451 25348397 28330616 association pull down ComPPI,IntAct
PA2G4 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
HPRT1 PA2G4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DDA1 PA2G4 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF20 PA2G4 25348397 N/A physical interaction ComPPI
PA2G4 PDIA6 24234451 30021884 physical association cross-linking study IntAct
PA2G4 MYBPC2 24234451 30021884 physical association cross-linking study IntAct
PA2G4 CETN3 24234451 30021884 physical association cross-linking study IntAct
PA2G4 TARBP1 24234451 30021884 physical association cross-linking study IntAct
PA2G4 HSPA5 24234451 30021884 physical association cross-linking study IntAct
PRKCA PA2G4 11325528 16642037 17316401 17951246 20068231 25691158 27898060 N/A N/A OmniPath
PRKCB PA2G4 11325528 20068231 27898060 N/A N/A OmniPath
PRKCD PA2G4 21145366 27898060 stimulant N/A OmniPath
PRKCG PA2G4 11325528 20068231 27898060 N/A N/A OmniPath
FUS PA2G4 19946338 27898060 stimulant N/A OmniPath
PAK1 PA2G4 18283314 27898060 stimulant N/A OmniPath

Visualization