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GENE：RASSF5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RASSF5
FullNmae Ras association domain family member 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17609
EnsembleID ENSG00000266094
Uniprot Q8WWW0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RASSF5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RASSF5 GO:0005515,GO:0005634,GO:0005737,GO:0005874,GO:0006915,GO:0007165,GO:0031398,GO:0046651,GO:0046872,GO:0050672,GO:1900180

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RASSF5 hsa:83593 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
RASSF5 hsa:83593 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
RASSF5 hsa:83593 path:hsa04218 Cellular senescence - Homo sapiens (human)
RASSF5 hsa:83593 path:hsa04670 Leukocyte transendothelial migration - Homo sapiens (human)
RASSF5 hsa:83593 path:hsa05200 Pathways in cancer - Homo sapiens (human)
RASSF5 hsa:83593 path:hsa05223 Non-small cell lung cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RASSF5 RAP2A 20005715 interaction type N/A PSP
RASSF5 RRAS 11857081 18988627 20005715 interaction type N/A PSP,SignaLink
RASSF5 RRAS2 20005715 interaction type N/A PSP
RASSF5 RAP1A 20005715 interaction type N/A PSP,SignaLink
RASSF5 STK3 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
AR RASSF5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 RASSF5 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RASSF5 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 RASSF5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 RASSF5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 RASSF5 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 RASSF5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 RASSF5 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 RASSF5 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00001EFEC1 RASSF5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 RASSF5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000006FDD4 RASSF5 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 RASSF5 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C RASSF5 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D RASSF5 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 RASSF5 25416803 28290615 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
KRAS RASSF5 11857081 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RABIF RASSF5 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP4-2 RASSF5 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RASSF5 SMAD4 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RASSF5 KRT40 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RASSF5 RAP2B 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RASSF5 APPBP2 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach ComPPI,IntAct
RASSF5 RRAS 11857081 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RASSF5 RAP1B 14525934 24234451 25348397 25416956 9488663 physical association experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
RASSF5 RAP2A 11857081 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
RASSF5 RALA 14525934 25348397 9488663 N/A two hybrid,two hybrid ComPPI,HPRD
RASSF5 HRAS 14525934 18596699 24234451 25348397 9488663 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,nuclear magnetic resonance,physical interaction,in vitro ComPPI,HPRD,IntAct
RASSF5 RRAS2 11857081 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RASSF5 STK4 11864565 14525934 15109305 16892067 20562859 23455922 24234451 24255178 24366813 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,coimmunoprecipitation,cross-linking study,experimental interaction detection,molecular sieving,nuclear magnetic resonance,physical interaction,in vivo,tandem affinity purification,proximity-dependent biotin identification ComPPI,HPRD,IntAct
RASSF5 RASSF1 11857081 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RASSF5 MRAS 11857081 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RASSF5 TERF2IP 12845325 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RASSF5 UBQLN1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
RASSF5 NRAS 14525934 25348397 9488663 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
RASSF5 RASSF2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RASSF5 MAP1LC3A 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RASSF5 MAP1LC3B 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
RASSF5 MAP1S 20562859 24234451 24366813 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RASSF5 MAP1B 20562859 24234451 24366813 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RASSF5 STK3 20562859 21988832 23455922 23972470 24234451 24255178 24366813 25348397 27898060 colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,molecular sieving,pull down,x-ray crystallography,physical interaction,protein kinase assay,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct,OmniPath
RASSF5 FLNC 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RASSF5 ERP44 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RASSF5 AGL 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RASSF5 KCTD12 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RASSF5 HIPK1 22173032 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RASSF5 MDM2 22173032 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RASSF5 ITCH 23538446 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RASSF5 KPNB1 25348397 N/A physical interaction ComPPI
RASSF5 ADH6 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RASSF5 LSM7 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RASSF5 MOB1A 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RASSF5 MOB1B 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RASSF5 BTRC 24234451 25217643 25348397 25416956 27898060 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
RASSF5 REL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RASSF5 TRAF1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RASSF5 TRAF2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RASSF5 MYLIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RASSF5 VPS28 25348397 N/A two hybrid,physical interaction ComPPI
RASSF5 AMOTL2 25348397 N/A physical interaction ComPPI
RASSF5 RAP1A 12845325 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
RASSF5 SAV1 25348397 N/A two hybrid ComPPI
RASSF5 RASSF4 25348397 N/A two hybrid ComPPI
RASSF5 GABARAP 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
RASSF5 GABARAPL1 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
RASSF5 GABARAPL2 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
RASSF5 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
RASSF5 RASSF5 11857081 14525934 20562859 24234451 physical association anti tag coimmunoprecipitation,experimental interaction detection HPRD,IntAct
RASSF5 RASSF1 11857081 16713569 22195963 27898060 stimulant N/A OmniPath
RASSF5 KRAS 11857081 22195963 27898060 stimulant N/A OmniPath

Visualization










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