Gene Information gene info

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GENE：USE1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol USE1
FullNmae unconventional SNARE in the ER 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30882
EnsembleID ENSG00000053501
Uniprot Q9NZ43

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
USE1 lysosomal_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
USE1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
USE1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
USE1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
USE1 GO:0005484,GO:0005515,GO:0005783,GO:0005783,GO:0005789,GO:0006890,GO:0007041,GO:0015031,GO:0030137,GO:0030163,GO:0031201,GO:0032940,GO:0061025

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
USE1 hsa:55850 path:hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP USE1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 USE1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
EGR1 USE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS USE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A USE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF USE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 USE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 USE1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000000B1C9 USE1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
HNRNPK USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CCDC70 USE1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX12 USE1 25348397 N/A physical interaction ComPPI
MEOX2 USE1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LMNA USE1 25348397 N/A physical interaction ComPPI
RINT1 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
JAGN1 USE1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ARHGEF2 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PRMT1 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RBM14 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPU USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
DDX5 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PABPC1 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
STX4 USE1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HNRNPA2B1 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
NSF USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
STX1A USE1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NAPA USE1 25348397 N/A physical interaction ComPPI
POLR2A USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CREB3 USE1 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
STX7 USE1 25348397 N/A physical interaction ComPPI
DDX3X USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EBP USE1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HNRNPUL1 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
BNIP1 USE1 12853481 15958492 19369418 21550981 24234451 25348397 27898060 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
CARM1 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPF USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
TIAL1 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPR USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
TFG USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ILF2 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
STX5 USE1 25348397 N/A physical interaction ComPPI
HNRNPD USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
TRIM27 USE1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HNRNPAB USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SEC22B USE1 25348397 N/A physical interaction ComPPI
SCFD1 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
VAMP4 USE1 25348397 N/A physical interaction ComPPI
ZW10 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
DDX4 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPA3 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SEC23A USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SEC24C USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
IVNS1ABP USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SCN3B USE1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HNRNPA0 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HSPD1 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RPSA USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ACTA2 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPH3 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPA1 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
STX18 USE1 19369418 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
DNAJC10 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
BSCL2 USE1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
USE1 APP 25348397 N/A physical interaction ComPPI
USE1 MGLL 25348397 N/A physical interaction ComPPI
USE1 SCFD2 25348397 N/A physical interaction ComPPI
USE1 NBAS 19369418 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
USE1 TYW5 25348397 N/A physical interaction ComPPI
USE1 C19ORF25 25348397 N/A physical interaction ComPPI
USE1 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
USE1 PCDHB7 25348397 N/A physical interaction ComPPI
USE1 TRMT61A 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
USE1 TRMT6 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
USE1 RPS3 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
USE1 AIFM2 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
USE1 HNRNPDL 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
USE1 ISYNA1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
USE1 PRPF39 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
USE1 APOL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
USE1 MFSD14B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
USE1 CALN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
USE1 CCM2L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
USE1 AQP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMEM86B USE1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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