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GENE：SPINT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPINT1
FullNmae serine peptidase inhibitor, Kunitz type 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11246
EnsembleID ENSG00000166145
Uniprot O43278

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPINT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SPINT1 GO:0001843,GO:0004867,GO:0005576,GO:0005615,GO:0005737,GO:0005886,GO:0008544,GO:0016020,GO:0030198,GO:0045687,GO:0060429,GO:0060670,GO:0060674,GO:0070062,GO:0071773,GO:2000178

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SPINT1 hsa:6692 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)
SPINT1 hsa:6692 path:hsa05215 Prostate cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 SPINT1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SPINT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SPINT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SPINT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SPINT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SPINT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SPINT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SPINT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SPINT1 N/A trascriptional regulation,stimulation inferred by curator TFlink
EGR2 SPINT1 N/A trascriptional regulation,stimulation inferred by curator TFlink
EGR3 SPINT1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
TENT5A SPINT1 14525934 15231748 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
ST14 SPINT1 10373425 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
SPINT1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct

Visualization










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