GENE:CAP1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CAP1 |
| FullNmae | cyclase associated actin cytoskeleton regulatory protein 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:20040 |
| EnsembleID | ENSG00000131236 |
| Uniprot | Q01518 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CAP1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CAP1 | GO:0000902,GO:0001667,GO:0003779,GO:0005515,GO:0005576,GO:0005737,GO:0005886,GO:0005925,GO:0006898,GO:0007015,GO:0007163,GO:0007165,GO:0007190,GO:0008179,GO:0019933,GO:0030864,GO:0035578,GO:0070062 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CAP1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | CAP1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | CAP1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | CAP1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | CAP1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | CAP1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | CAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | CAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | CAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000122ED0 | CAP1 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00004505E4 | CAP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00005651EE | CAP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000183BED | CAP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000DDD35 | CAP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002075FA | CAP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000D5FFC | CAP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ACTG1 | CAP1 | 11950878 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| CFL1 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| MCM5 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| ACTB | CAP1 | 14525934 25348397 8761950 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
| MCM6 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| MCM2 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| HSP90AB1 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| JUN | CAP1 | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| LIG4 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| U2AF2 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| DLD | CAP1 | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| HSP90AA1 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| FMNL1 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| HSP90B1 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| PXN | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| SERPINB8 | CAP1 | 14525934 25348397 8761950 | N/A | two hybrid,experimental interaction detection,in vivo,two hybrid | ComPPI,HPRD |
| CFTR | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| TPM3 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| ABI2 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| SIRT1 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| PLA2G4A | CAP1 | 18330356 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| HTRA2 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| BARD1 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| PSME2 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| NEK9 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| MCM3 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| MCM4 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| BRCA1 | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
| MYOC | CAP1 | 14525934 16289162 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| CAP1 | CAP2 | 14525934 25348397 8761950 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
| CAP1 | UCHL5 | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | SIRT7 | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | MYL12B | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | FN1 | 19738201 24234451 25348397 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| CAP1 | SHTN1 | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | TPM4 | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | OGA | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | UFD1 | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | DPH2 | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | DPYSL2 | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | NPLOC4 | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | RNASEH2C | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | ACTA1 | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | BCL7A | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | TWF2 | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | ACTA2 | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | BCL7C | 25348397 | N/A | physical interaction | ComPPI |
| CAP1 | G3BP1 | 25348397 | N/A | physical interaction | ComPPI |
| ATF2 | CAP1 | 22304920 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FASN | CAP1 | 25348397 | N/A | physical interaction | ComPPI |
