Gene Information gene info

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GENE：HACD1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HACD1
FullNmae 3-hydroxyacyl-CoA dehydratase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9639
EnsembleID ENSG00000165996
Uniprot B0YJ81

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HACD1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HACD1 GO:0005515,GO:0005789,GO:0018812,GO:0018812,GO:0030148,GO:0030497,GO:0035338,GO:0042761

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HACD1 hsa:9200 path:hsa00062 Fatty acid elongation - Homo sapiens (human)
HACD1 hsa:9200 path:hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human)
HACD1 hsa:9200 path:hsa01100 Metabolic pathways - Homo sapiens (human)
HACD1 hsa:9200 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 HACD1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 HACD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HACD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HACD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HACD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HACD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A HACD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HACD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 HACD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000013DD8 HACD1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
RPN1 HACD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
LMNA HACD1 25348397 N/A physical interaction ComPPI
UBC HACD1 25348397 N/A physical interaction ComPPI
PHB HACD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
SEMG1 HACD1 25348397 N/A physical interaction ComPPI
SEMG2 HACD1 25348397 N/A physical interaction ComPPI
XPO1 HACD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
PHB2 HACD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
CSE1L HACD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
ATP2B1 HACD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
ATP2A2 HACD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
TPM4 HACD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
GNB1 HACD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
RPN2 HACD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
CORO1C HACD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
TECR HACD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HACD1 SLC15A1 25348397 N/A physical interaction ComPPI

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