Gene Information gene info

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GENE：KRIT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KRIT1
FullNmae KRIT1 ankyrin repeat containing
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1573
EnsembleID ENSG00000001631
Uniprot O00522

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KRIT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
KRIT1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KRIT1 GO:0001525,GO:0001937,GO:0003158,GO:0005515,GO:0005546,GO:0005615,GO:0005737,GO:0005856,GO:0005886,GO:0005886,GO:0005911,GO:0007264,GO:0008017,GO:0010596,GO:0016525,GO:0016525,GO:0030695,GO:0032991,GO:0033622,GO:0045454,GO:0045454,GO:0045765,GO:2000114,GO:2000114,GO:2000352

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KRIT1 hsa:889 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
KRIT1 hsa:889 path:hsa04520 Adherens junction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CCM2 KRIT1 16037064 23180781 physical association anti tag coimmunoprecipitation,fluorescent resonance energy transfer InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 KRIT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP73 KRIT1 19558638 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 KRIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KRIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KRIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 KRIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D KRIT1 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PDCD10 KRIT1 17657516 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TRPV4 KRIT1 25348397 N/A physical interaction ComPPI
RGS4 KRIT1 10747990 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PLCB1 KRIT1 25348397 N/A physical interaction ComPPI
ITGB1BP1 KRIT1 11741838 11854171 14525934 24234451 25348397 25814554 25910212 27898060 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid bait and prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct,OmniPath
RAP1A KRIT1 14525934 25348397 9285558 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
KRIT1 DAPK1 25348397 N/A physical interaction ComPPI
KRIT1 RCHY1 25348397 N/A physical interaction ComPPI
KRIT1 PLCB3 12821674 25348397 27898060 N/A physical interaction ComPPI,OmniPath
KRIT1 PIK3C3 25348397 N/A physical interaction ComPPI
KRIT1 PIK3R4 25348397 N/A physical interaction ComPPI
KRIT1 FAS 14594800 25348397 27898060 N/A physical interaction ComPPI,OmniPath
KRIT1 RAP1B 25348397 N/A physical interaction ComPPI
KRIT1 NXF1 25348397 N/A physical interaction ComPPI
KRIT1 CCM2 17657516 23007647 24234451 25348397 25814554 25910212 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
KRIT1 HEG1 23007647 24234451 25348397 physical association affinity chromatography technology,isothermal titration calorimetry,pull down,x-ray crystallography,physical interaction ComPPI,IntAct
KRIT1 SLC34A2 25348397 N/A physical interaction ComPPI
KRIT1 UBFD1 25348397 N/A physical interaction ComPPI
KRIT1 UBE2K 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRIT1 SNX17 25059659 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B29D0 KRIT1 27087310 direct interaction,inhibition N/A NPInter
URS00009AF46A KRIT1 27087310 direct interaction,inhibition N/A NPInter

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