GENE：APOBEC1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | APOBEC1 |
| FullNmae | apolipoprotein B mRNA editing enzyme catalytic subunit 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:604 |
| EnsembleID | ENSG00000111701 |
| Uniprot | P41238 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| APOBEC1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| APOBEC1 | GO:0003723,GO:0004126,GO:0004126,GO:0004126,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0006397,GO:0006629,GO:0006641,GO:0008270,GO:0009972,GO:0010332,GO:0016554,GO:0016554,GO:0016554,GO:0016556,GO:0030895,GO:0035925,GO:0042127,GO:0042158,GO:0042953,GO:0045293,GO:0048255,GO:0051649,GO:0080111,GO:0080111,GO:0090209,GO:0090310,GO:0140098,GO:1901537,GO:2000623 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GATA2 | APOBEC1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | APOBEC1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | APOBEC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | APOBEC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | APOBEC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | APOBEC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | APOBEC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | APOBEC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | APOBEC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | APOBEC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| KPNA2 | APOBEC1 | 12881431 14525934 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| HNRNPK | APOBEC1 | 25348397 | N/A | two hybrid | ComPPI |
| HNRNPC | APOBEC1 | 25348397 | N/A | two hybrid | ComPPI |
| CDK6 | APOBEC1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SYNCRIP | APOBEC1 | 25348397 | N/A | physical interaction | ComPPI |
| BAG4 | APOBEC1 | 14525934 14559896 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| APOBEC1 | DNAJB11 | 11584023 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| HNRNPF | APOBEC1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MAPK1 | APOBEC1 | 11463337 27898060 | N/A | N/A | OmniPath |