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GENE：MSH5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MSH5
FullNmae mutS homolog 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7328
EnsembleID ENSG00000204410
Uniprot O43196

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MSH5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MSH5 GO:0003690,GO:0005515,GO:0005524,GO:0005634,GO:0006298,GO:0030983,GO:0051026,GO:0140664

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR MSH5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 MSH5 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MSH5 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F1 MSH5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MSH5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MSH5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000568FF8 MSH5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000759B6A MSH5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 MSH5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 MSH5 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
XRCC5 MSH5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPL MSH5 25348397 N/A physical interaction ComPPI
XPO1 MSH5 25348397 N/A physical interaction ComPPI
MSH4 MSH5 10029069 12591739 14525934 16122992 16397227 22401567 24234451 25348397 27898060 9374523 9787078 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,protein three hybrid,in vitro,two hybrid ComPPI,HPRD,IntAct,OmniPath
GPS2 MSH5 25348397 N/A physical interaction ComPPI
MSH5 ABL1 16397227 19442657 22401567 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,pull down,physical interaction,protein three hybrid,tandem affinity purification ComPPI,IntAct
MSH5 FANCA 25348397 N/A physical interaction ComPPI
MSH5 LRRK2 24234451 24725412 25348397 association tandem affinity purification ComPPI,IntAct
ABL1 MSH5 16397227 19442657 20841568 22401567 27898060 N/A N/A OmniPath

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