GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
CTSE
FullNmae
cathepsin E
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:2530
EnsembleID
ENSG00000196188
Uniprot
P14091
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
CTSE
lysosomal_cd
36341760
220 lysosome-dependent cell death genes.
retulator signature
CTSE
lysosomal_cd
36341760
The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
CTSE
immunogenic
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
Go Annotation:
GeneSymbol
Go id
CTSE
GO:0004190,GO:0004190,GO:0005768,GO:0005768,GO:0006508,GO:0006508,GO:0008233,GO:0016540,GO:0019886,GO:0019886,GO:0042802,GO:0043231
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
YBX1
CTSE
19151767
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
SMARCA4
CTSE
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
CTSE
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
CTSE
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
CTSE
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
SPI1
CTSE
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
A2M
CTSE
25361965
interaction type
N/A
PTMCode2
CTSE
A2M
25361965
interaction type
N/A
PTMCode2
Source
Target
Pmid
Interactiontype
Methods
Database
KCTD6
CTSE
25348397
N/A
physical interaction
ComPPI
INS
CTSE
14525934
195962
1959628
25348397
27898060
N/A
experimental interaction detection,in vitro
ComPPI,HPRD,OmniPath
BAG6
CTSE
14525934
16169070
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid
ComPPI,HPRD,IntAct
CHEK1
CTSE
25348397
N/A
physical interaction
ComPPI
CCNT1
CTSE
25348397
N/A
physical interaction
ComPPI
EDN3
CTSE
14525934
2226872
25348397
27898060
N/A
experimental interaction detection,in vitro
ComPPI,HPRD,OmniPath
GNB2
CTSE
25348397
N/A
physical interaction
ComPPI
MTMR6
CTSE
25348397
N/A
physical interaction
ComPPI
MTMR9
CTSE
25348397
N/A
physical interaction
ComPPI
CTSE
EMG1
14525934
16169070
24234451
25348397
physical association
two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid
ComPPI,HPRD,IntAct
CTSE
A2M
12631277
14525934
25348397
27898060
N/A
experimental interaction detection,in vitro
ComPPI,HPRD,OmniPath
CTSE
B3GLCT
25348397
N/A
physical interaction
ComPPI
CTSE
CTSE
14525934
15342244
N/A
experimental interaction detection
HPRD
Visualization