Gene Information gene info

GENE:PBX2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PBX2
FullNmae PBX homeobox 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8633
EnsembleID ENSG00000204304
Uniprot P40425

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PBX2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PBX2 GO:0000785,GO:0000977,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0001654,GO:0003682,GO:0005515,GO:0005634,GO:0005667,GO:0006357,GO:0007420,GO:0009887,GO:0009954,GO:0030326,GO:0045944,GO:0048568,GO:0048666,GO:0140297

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ELP1 PBX2 14667819 23180781 physical association two hybrid InnateDB
HOXA9 PBX2 10082572 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB

Source Target Pmid Interactiontype Methods Database
FOS PBX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PBX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PBX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000512C88 PBX2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000236310 PBX2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000A939F PBX2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002367FA PBX2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 PBX2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000F4AC3 PBX2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 PBX2 22964640 25416803 26701625 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000324096 PBX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000A07C1 PBX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000B1C9 PBX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029979D PBX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237CBD PBX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002373FD PBX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003D8730 PBX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000033B548 PBX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BE495 PBX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032EF64 PBX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004929F1 PBX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122ED0 PBX2 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FAM90A1 PBX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAB21L2 PBX2 25348397 N/A physical interaction ComPPI
HOXA1 PBX2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HOXB5 PBX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MEIS2 PBX2 25348397 N/A physical interaction ComPPI
BFSP2 PBX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUP62 PBX2 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PBX2 RPL4 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PBX2 BLOC1S1 14667819 24234451 25348397 physical association two hybrid ComPPI,IntAct
PBX2 PKNOX1 14525934 19559479 24234451 25348397 9482739 physical association two hybrid,experimental interaction detection,physical interaction,imaging technique,in vivo ComPPI,HPRD,IntAct
PBX2 UBE2E1 14525934 14667819 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
PBX2 ELP1 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PBX2 BAIAP2 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PBX2 DCTN3 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PBX2 CENPBD1 14525934 14667819 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
PBX2 PBX1 14525934 24234451 25348397 9482739 N/A experimental interaction detection,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct
PBX2 RPS6KC1 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PBX2 CCDC88B 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PBX2 MCRS1 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PBX2 SMYD3 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PBX2 MTREX 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PBX2 ZDHHC7 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PBX2 COPS6 14525934 14667819 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PBX2 HOXA9 10082572 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PBX2 HOXB8 11438208 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
PBX2 ELAVL1 25348397 N/A physical interaction ComPPI
PBX2 SOX2 25348397 N/A physical interaction ComPPI
PBX2 CARD9 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PBX2 SHMT2 25348397 N/A physical interaction ComPPI
PBX2 MOV10 25348397 N/A physical interaction ComPPI
PBX2 LMX1B 25348397 N/A physical interaction ComPPI
PBX2 MAGEA1 25348397 N/A physical interaction ComPPI
PBX2 MAB21L1 25348397 N/A physical interaction ComPPI
PBX2 CREB1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PBX2 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PBX2 FOXE1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PBX2 FOXI2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PBX2 FOXS1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PBX2 TRAF1 25348397 N/A physical interaction ComPPI
PBX2 FAM222A 25348397 N/A physical interaction ComPPI
PBX2 CCDC120 25348397 N/A physical interaction ComPPI
PBX2 C5ORF24 25348397 N/A physical interaction ComPPI
PBX2 DNAAF8 25348397 N/A physical interaction ComPPI
PBX2 VWA5A 25348397 N/A physical interaction ComPPI
PBX2 COL20A1 25348397 N/A physical interaction ComPPI
PBX2 WDR4 25348397 N/A physical interaction ComPPI
PBX2 TMOD3 25348397 N/A physical interaction ComPPI
PBX2 SRPRB 25348397 N/A physical interaction ComPPI
PBX2 PLEKHA1 25348397 N/A physical interaction ComPPI
PBX2 KRBA1 25348397 N/A physical interaction ComPPI
PBX2 AFF4 25348397 N/A physical interaction ComPPI
PBX2 STK25 25348397 N/A physical interaction ComPPI
PBX2 HNRNPL 25348397 N/A physical interaction ComPPI
PBX2 TLX1 19559479 24234451 25348397 physical association two hybrid ComPPI,IntAct
PBX2 HOXA5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 BRMS1L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 MSC 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 EFHC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 CDCA7L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 HOXC8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 ZNF587 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 RIPPLY2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 BLOC1S5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 ZCWPW2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 PPFIBP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 HOXC5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HOXC9 PBX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX2 PBX2 10082572 14525934 N/A experimental interaction detection HPRD

Source Target Pmid Interactiontype Methods Database
URS000008CE2D PBX2 27087310 direct interaction,inhibition N/A NPInter

Visualization