GENE：CA8
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CA8 |
| FullNmae | carbonic anhydrase 8 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1382 |
| EnsembleID | ENSG00000178538 |
| Uniprot | P35219 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CA8 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CA8 | GO:0004089,GO:0005515,GO:0005737,GO:0006730,GO:0008270,GO:0016836,GO:0048015 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CA8 | hsa:767 | path:hsa00910 | Nitrogen metabolism - Homo sapiens (human) |
| CA8 | hsa:767 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | CA8 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | CA8 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | CA8 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | CA8 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CA8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CA8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CA8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CA8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CA8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CA8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CA8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | CA8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000F31F4 | CA8 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | CA8 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00001EFEC1 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000285DCB | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000393C7 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001B9F58 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AD231 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000002CF68 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000412AC7 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000759EB8 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002233F4 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A71AD | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C3AC1 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F6E49 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000427B68 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | CA8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002AB575 | CA8 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000100748 | CA8 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | CA8 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | CA8 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000028DE3F | CA8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001067D1 | CA8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002CEB74 | CA8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CA8 | CRX | 24234451 25348397 25416956 25910212 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid | ComPPI,IntAct |
| CA8 | GGA2 | 24234451 25348397 25416956 25910212 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid | ComPPI,IntAct |
| CA8 | ITPR1 | 12611586 14525934 25348397 26186194 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| CA8 | TBX3 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| CA8 | MAGED1 | 24234451 25348397 25416956 25910212 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid | ComPPI,IntAct |
| CA8 | SPDL1 | 24234451 25348397 25416956 25910212 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid | ComPPI,IntAct |
| CA8 | LNX1 | 24234451 25348397 25416956 25910212 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid | ComPPI,IntAct |
| CA8 | KLK7 | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | ALB | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | ITPR2 | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | TF | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | SERPINA1 | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | PKP1 | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | S100A7 | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | ECM1 | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | IGLL5 | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | FGG | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | STAT3 | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array,validated two hybrid | ComPPI,IntAct |
| CA8 | AHSG | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | C3 | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | CDSN | 25348397 | N/A | physical interaction | ComPPI |
| CA8 | LMNB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |