Gene Information gene info

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GENE：DOCK6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DOCK6
FullNmae dedicator of cytokinesis 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19189
EnsembleID ENSG00000130158
Uniprot Q96HP0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DOCK6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DOCK6 GO:0005085,GO:0005515,GO:0005829,GO:0005829,GO:0005829,GO:0007264,GO:0043547,GO:0048471

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR DOCK6 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 DOCK6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DOCK6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DOCK6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DOCK6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DOCK6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 DOCK6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DOCK6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DOCK6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 DOCK6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 DOCK6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 DOCK6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 DOCK6 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000CF1D2 DOCK6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001E0AEA DOCK6 25416803 25832008 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
AKT1 DOCK6 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
DOCK7 DOCK6 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CLU DOCK6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBC DOCK6 25348397 N/A physical interaction ComPPI
LRP8 DOCK6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB32 DOCK6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPL DOCK6 25348397 N/A physical interaction ComPPI
RAB2A DOCK6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPO1 DOCK6 25348397 N/A physical interaction ComPPI
DOCK8 DOCK6 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TADA2A DOCK6 25348397 N/A physical interaction ComPPI
MOB1A DOCK6 24234451 24255178 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
LRCH3 DOCK6 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF7 DOCK6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DOCK6 CRLF3 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DOCK6 MOB1B 24234451 24255178 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DOCK6 MYH6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DOCK6 REEP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DOCK6 SLC33A1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DOCK6 RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DOCK6 ZNF785 25348397 N/A physical interaction ComPPI
DOCK6 ZNF331 25348397 N/A physical interaction ComPPI
FLNC DOCK6 24234451 30021884 physical association cross-linking study IntAct
HNRNPA1L2 DOCK6 24234451 30021884 physical association cross-linking study IntAct

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