Gene Information gene info

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GENE：GLDC

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GLDC
FullNmae glycine decarboxylase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4313
EnsembleID ENSG00000178445
Uniprot P23378

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GLDC immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GLDC GO:0004375,GO:0004375,GO:0005654,GO:0005739,GO:0005739,GO:0005759,GO:0005886,GO:0005960,GO:0006546,GO:0009055,GO:0016594,GO:0016829,GO:0019464,GO:0022900,GO:0030170,GO:0036255,GO:0042803,GO:0070280,GO:1903442,GO:1990830

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GLDC hsa:2731 path:hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human)
GLDC hsa:2731 path:hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human)
GLDC hsa:2731 path:hsa00785 Lipoic acid metabolism - Homo sapiens (human)
GLDC hsa:2731 path:hsa01100 Metabolic pathways - Homo sapiens (human)
GLDC hsa:2731 path:hsa01200 Carbon metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TLR10 GLDC 16482509 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR GLDC 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 GLDC 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 GLDC 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
NR1I2 GLDC 19129222 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 GLDC 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 GLDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GLDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GLDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GLDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GLDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GLDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GLDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 GLDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GLDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000BE495 GLDC 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
TNFAIP3 GLDC 25348397 N/A physical interaction ComPPI
JUN GLDC 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
NTRK1 GLDC 25348397 N/A physical interaction ComPPI
CUL2 GLDC 25348397 N/A physical interaction ComPPI
FDPS GLDC 25348397 N/A physical interaction ComPPI
SNU13 GLDC 25348397 N/A physical interaction ComPPI
SUZ12 GLDC 25348397 N/A physical interaction ComPPI
ULK2 GLDC 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GLDC TLR10 14525934 16482509 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
GLDC NUDT6 25348397 N/A physical interaction ComPPI
GLDC MRM1 25348397 N/A physical interaction ComPPI
GLDC NDUFAB1 25348397 N/A physical interaction ComPPI
GLDC OXLD1 25348397 N/A physical interaction ComPPI
GLDC SPATA13 25348397 N/A physical interaction ComPPI
GLDC SOST 25348397 N/A physical interaction ComPPI
GLDC POLG2 25348397 N/A physical interaction ComPPI
GLDC CAPN6 25348397 N/A physical interaction ComPPI
GLDC TNIP3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
GLDC MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GLDC PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
COX4I1 GLDC 25348397 N/A physical interaction ComPPI
HSCB GLDC 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
GLDC GLDC 14525934 6778858 N/A experimental interaction detection HPRD

Visualization










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