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GENE：HMBOX1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HMBOX1
FullNmae homeobox containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26137
EnsembleID ENSG00000147421
Uniprot Q6NT76

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HMBOX1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HMBOX1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HMBOX1 GO:0000122,GO:0000781,GO:0000781,GO:0000785,GO:0003691,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005829,GO:0015030,GO:0016604,GO:0016605,GO:0032212,GO:0032212,GO:0035563,GO:0042162,GO:0042162,GO:0042802,GO:0043565,GO:0044877,GO:0045892,GO:0045893,GO:0051972,GO:0051973,GO:0051973,GO:1990837

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BYSL HMBOX1 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR HMBOX1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HMBOX1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 HMBOX1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 HMBOX1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 HMBOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HMBOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HMBOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HMBOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HMBOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HMBOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HMBOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 HMBOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000019907A HMBOX1 22320217 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 HMBOX1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000171CD1 HMBOX1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C HMBOX1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D HMBOX1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001EB9FC HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 HMBOX1 19536157 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000045E0EC HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000572E11 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000028D811 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D HMBOX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 HMBOX1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 HMBOX1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D HMBOX1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 HMBOX1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000358C16 HMBOX1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001E96DA HMBOX1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000054DF42 HMBOX1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FARS2 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MFAP1 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BYSL HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZNF581 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PIAS2 HMBOX1 25348397 N/A two hybrid ComPPI
SNRPB2 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SNW1 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MORF4L2 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM90A1 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZMAT2 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FNDC11 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CBX8 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DYNLL1 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP5PO HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA2 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FXR2 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RPL9 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DYNLL2 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
IPO13 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COIL HMBOX1 23685356 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,fluorescence microscopy ComPPI,IntAct
TP53BP1 HMBOX1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
LMNA HMBOX1 24234451 25348397 29568061 association pull down ComPPI,IntAct
MRPL28 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAGEH1 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
INO80B HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIM2 HMBOX1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
REEP6 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GNL3L HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZBTB26 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NOP10 HMBOX1 23685356 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
NHP2 HMBOX1 23685356 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PICK1 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WT1 HMBOX1 25348397 N/A physical interaction ComPPI
MEOX1 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAA1 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DAB1 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
XRCC5 HMBOX1 23685356 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ZNF587 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DSCC1 HMBOX1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XRCC6 HMBOX1 23685356 24234451 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPL HMBOX1 25348397 N/A physical interaction ComPPI
PKM HMBOX1 25348397 N/A protein kinase assay ComPPI
SDCBP HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBA6 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MORF4L1 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RPS25 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LMO1 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MCRS1 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MED23 HMBOX1 25348397 N/A physical interaction ComPPI
BRD1 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCNG1 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MDC1 HMBOX1 25348397 N/A physical interaction ComPPI
PIP4K2B HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PAX6 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDC7 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GAR1 HMBOX1 23685356 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
BRCA1 HMBOX1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
GSC2 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ENTPD2 HMBOX1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AEBP2 HMBOX1 25348397 N/A physical interaction ComPPI
CARD9 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LNX1 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRPF18 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DNTTIP1 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KAT5 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FRMD6 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VPS72 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CDK18 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DKC1 HMBOX1 23685356 24234451 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
SH2D4A HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SCNM1 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ENKD1 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZNF417 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZBTB24 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
IFFO1 HMBOX1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2Z HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZNF337 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DPF2 HMBOX1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
C8ORF33 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SAP30L HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MEMO1 HMBOX1 25348397 N/A physical interaction ComPPI
APP HMBOX1 25348397 N/A physical interaction ComPPI
PAX5 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TCEANC HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TCEA2 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM13C HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FAM161A HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AMOTL1 HMBOX1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PYHIN1 HMBOX1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
ASB7 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
COBLL1 HMBOX1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MRPL11 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SFR1 HMBOX1 25348397 N/A physical interaction ComPPI
FAM217B HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GAS2L2 HMBOX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HMBOX1 FAM117A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HMBOX1 CDADC1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HMBOX1 NPIPA7 24234451 25348397 25416956 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HMBOX1 FAM74A4 24234451 25348397 25416956 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HMBOX1 KIF9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HMBOX1 FGF11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HMBOX1 TSGA10IP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ABITRAM HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HMBOX1 HMBOX1 24234451 25416956 physical association two hybrid array,two hybrid prey pooling approach IntAct

Source Target Pmid Interactiontype Methods Database
URS00008B6A5F HMBOX1 27087310 direct interaction,inhibition N/A NPInter

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