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GENE：HSD11B2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HSD11B2
FullNmae hydroxysteroid 11-beta dehydrogenase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5209
EnsembleID ENSG00000176387
Uniprot P80365

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HSD11B2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HSD11B2 GO:0001666,GO:0002017,GO:0005496,GO:0005789,GO:0007565,GO:0008211,GO:0009410,GO:0032094,GO:0032868,GO:0034650,GO:0043231,GO:0043231,GO:0051287,GO:0051384,GO:0070523,GO:0070523

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HSD11B2 hsa:3291 path:hsa00140 Steroid hormone biosynthesis - Homo sapiens (human)
HSD11B2 hsa:3291 path:hsa01100 Metabolic pathways - Homo sapiens (human)
HSD11B2 hsa:3291 path:hsa04960 Aldosterone-regulated sodium reabsorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MYC HSD11B2 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 HSD11B2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA HSD11B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HSD11B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HSD11B2 15659537 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HSD11B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HSD11B2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NF1 HSD11B2 17551100 trascriptional regulation,stimulation inferred by curator TFlink
NFIC HSD11B2 17551100 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 HSD11B2 15659537 trascriptional regulation,stimulation inferred by curator TFlink
NR3C1 HSD11B2 17551100 trascriptional regulation,stimulation inferred by curator TFlink
PPARD HSD11B2 15591138 trascriptional regulation,stimulation inferred by curator TFlink
RELA HSD11B2 15659537 trascriptional regulation,stimulation inferred by curator TFlink
SP1 HSD11B2 17551100 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 HSD11B2 17551100 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CTBP1 HSD11B2 25361965 interaction type N/A PTMCode2
HSD11B2 CTBP1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CTBP1 HSD11B2 12082639 12878208 25348397 27898060 N/A physical interaction ComPPI,OmniPath
KAT2B HSD11B2 25348397 N/A physical interaction ComPPI
HNRNPL HSD11B2 25348397 N/A physical interaction ComPPI
KAT2A HSD11B2 25348397 N/A physical interaction ComPPI
BRAF HSD11B2 25348397 N/A physical interaction ComPPI
HDAC1 HSD11B2 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00008B89E1 HSD11B2 27087310 direct interaction,inhibition N/A NPInter

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