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GENE：HSD17B7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HSD17B7
FullNmae hydroxysteroid 17-beta dehydrogenase 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5215
EnsembleID ENSG00000132196
Uniprot P56937

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HSD17B7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HSD17B7 GO:0000253,GO:0000253,GO:0000253,GO:0004303,GO:0004303,GO:0005789,GO:0005789,GO:0005789,GO:0006695,GO:0006695,GO:0006695,GO:0006703,GO:0006703,GO:0008209,GO:0047024,GO:0047024

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HSD17B7 hsa:51478 path:hsa00100 Steroid biosynthesis - Homo sapiens (human)
HSD17B7 hsa:51478 path:hsa00140 Steroid hormone biosynthesis - Homo sapiens (human)
HSD17B7 hsa:51478 path:hsa01100 Metabolic pathways - Homo sapiens (human)
HSD17B7 hsa:51478 path:hsa04913 Ovarian steroidogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MYCN HSD17B7 16093321 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 HSD17B7 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA HSD17B7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HSD17B7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 HSD17B7 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000338542 HSD17B7 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
POLB HSD17B7 25348397 N/A physical interaction ComPPI
SLAMF1 HSD17B7 25348397 N/A physical interaction ComPPI
BRSK1 HSD17B7 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SLC1A5 HSD17B7 25348397 N/A physical interaction ComPPI
DTYMK HSD17B7 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GORAB HSD17B7 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HSD17B7 SLC18A1 25348397 N/A physical interaction ComPPI
HSD17B7 SLC37A3 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00008C121E HSD17B7 27087310 direct interaction,inhibition N/A NPInter

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