Gene Information gene info

  1. Home

GENE：KMT2C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KMT2C
FullNmae lysine methyltransferase 2C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13726
EnsembleID ENSG00000055609
Uniprot Q8NEZ4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KMT2C immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KMT2C GO:0003677,GO:0003713,GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006338,GO:0016746,GO:0032259,GO:0035097,GO:0042054,GO:0042393,GO:0042800,GO:0042800,GO:0044666,GO:0044666,GO:0044666,GO:0045944,GO:0046872,GO:0051602,GO:0140945,GO:0140999

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KMT2C hsa:58508 path:hsa00310 Lysine degradation - Homo sapiens (human)
KMT2C hsa:58508 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR KMT2C 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 KMT2C 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 KMT2C 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 KMT2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KMT2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 KMT2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KMT2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 KMT2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 KMT2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 KMT2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 KMT2C 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 KMT2C 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000041FA2C KMT2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000019D79B KMT2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 KMT2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000013DD8 KMT2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 KMT2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE KMT2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD KMT2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 KMT2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000041CB9C KMT2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 KMT2C 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 KMT2C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F KMT2C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00006AA21F KMT2C 25416803 26472042 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
CDC73 KMT2C 19136632 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DPY30 KMT2C 25348397 N/A physical interaction ComPPI
RING1 KMT2C 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
JUN KMT2C 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MAPK14 KMT2C 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PAXIP1 KMT2C 17500065 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NCOA6 KMT2C 12482968 17021013 19047629 19433796 23870121 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ASH2L KMT2C 12482968 17500065 23870121 24234451 25348397 association,physical association anti bait coimmunoprecipitation,molecular sieving,pull down,physical interaction ComPPI,IntAct
HNRNPL KMT2C 25348397 N/A physical interaction ComPPI
RBBP5 KMT2C 12482968 17500065 24234451 25348397 26886794 association,physical association anti bait coimmunoprecipitation,molecular sieving,pull down,x-ray crystallography,physical interaction ComPPI,IntAct
SMARCB1 KMT2C 19221051 25348397 27898060 N/A physical interaction ComPPI,OmniPath
H3-4 KMT2C 25348397 N/A physical interaction ComPPI
H3C15 KMT2C 25348397 N/A physical interaction ComPPI
H3C1 KMT2C 25348397 N/A physical interaction ComPPI
FOXA1 KMT2C 25348397 N/A physical interaction ComPPI
H3-3A KMT2C 25348397 N/A physical interaction ComPPI
TRIM25 KMT2C 25348397 N/A physical interaction ComPPI
ELAVL1 KMT2C 25348397 N/A physical interaction ComPPI
WDR5 KMT2C 17500065 24234451 25348397 27705803 association,physical association anti bait coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
APPL2 KMT2C 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
MTNR1B KMT2C 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
AK1 KMT2C 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53 KMT2C 19433796 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CALR KMT2C 24234451 30021884 physical association cross-linking study IntAct
PABPC1 KMT2C 24234451 30021884 physical association cross-linking study IntAct
TCOF1 KMT2C 24234451 30021884 physical association cross-linking study IntAct

Visualization










  Return