Gene Information gene info

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GENE：MYO5B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MYO5B
FullNmae myosin VB
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7603
EnsembleID ENSG00000167306
Uniprot Q9ULV0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MYO5B pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MYO5B immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MYO5B GO:0000146,GO:0000146,GO:0003091,GO:0005515,GO:0005516,GO:0005524,GO:0005737,GO:0007015,GO:0015031,GO:0015629,GO:0016192,GO:0016197,GO:0016459,GO:0030050,GO:0030659,GO:0031267,GO:0031982,GO:0032991,GO:0045179,GO:0051015,GO:0055037,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MYO5B hsa:4645 path:hsa04814 Motor proteins - Homo sapiens (human)
MYO5B hsa:4645 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MYO5B CFTR 17462998 23180781 physical association anti tag coimmunoprecipitation InnateDB
MYO5B RAB11A 17462998 23180781 physical association anti tag coimmunoprecipitation InnateDB
BNIP2 MYO5B 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR MYO5B 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 MYO5B 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MYO5B 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 MYO5B 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A MYO5B 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXA1 MYO5B 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA MYO5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MYO5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MYO5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 MYO5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MYO5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MYO5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MYO5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000753AD MYO5B 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
COIL MYO5B 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PPP1CB MYO5B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAC1 MYO5B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RAB8A MYO5B 25348397 N/A physical interaction ComPPI
SYTL4 MYO5B 25348397 N/A physical interaction ComPPI
SMAD3 MYO5B 14525934 15527767 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PEX19 MYO5B 25348397 N/A physical interaction ComPPI
RAB3B MYO5B 25348397 N/A physical interaction ComPPI
IQGAP1 MYO5B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO18A MYO5B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CXCR2 MYO5B 14525934 15004234 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RAB11A MYO5B 11408590 11495908 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
EVI5 MYO5B 25348397 N/A physical interaction ComPPI
STX3 MYO5B 25348397 N/A physical interaction ComPPI
TRIM25 MYO5B 25348397 N/A physical interaction ComPPI
RAB11FIP2 MYO5B 11495908 12393859 14525934 16473632 18984164 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
SSH1 MYO5B 25348397 N/A physical interaction ComPPI
KIAA1549 MYO5B 12421765 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
MYO5B RAB25 11408590 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MYO5B PAN2 25348397 N/A physical interaction ComPPI
MYO5B POLR1C 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MYO5B BNIP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MYO5B TCF4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MYO5B AMOTL2 25348397 N/A physical interaction ComPPI
MYO5B TRIM54 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MYO5B CCDC8 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MYO5B LRRC39 25348397 N/A physical interaction ComPPI
MYO5B TMOD1 25348397 N/A physical interaction ComPPI
MYO5B CAPZB 25348397 N/A physical interaction ComPPI
MYO5B CAPZA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO5B DBN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO5B MYH9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO5B SYNPO 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO5B LIMA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO5B ANLN 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO5B MYO19 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO5B SKA3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO5B EXOC6 25348397 N/A physical interaction ComPPI
MYO5B TBC1D30 25348397 N/A physical interaction ComPPI
MYO5B TMOD3 25348397 N/A physical interaction ComPPI
MYO5B DKK3 25348397 N/A physical interaction ComPPI
MYO5B MYL2 25348397 N/A physical interaction ComPPI
MYO5B PPP6R2 25348397 N/A physical interaction ComPPI
MYO5B PDF 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MYO5B CD164 17673908 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
RAB11B MYO5B 11408590 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD

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