Gene Information gene info

  1. Home

GENE：PAX3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PAX3
FullNmae paired box 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8617
EnsembleID ENSG00000135903
Uniprot P23760

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PAX3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PAX3 GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0003700,GO:0005515,GO:0005654,GO:0005654,GO:0006357,GO:0006915,GO:0007399,GO:0007517,GO:0007605,GO:0009887,GO:0043565,GO:0045893,GO:0045944,GO:0048856,GO:0071837,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PAX3 hsa:5077 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PAX3 17011549 23180781 physical association anti tag coimmunoprecipitation InnateDB
PAX3 WNT1 23180781 25721714 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 PAX3 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 PAX3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA PAX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PAX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PAX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PAX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PAX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PAX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
POU3F2 PAX3 22290434 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 PAX3 19074888 trascriptional regulation,stimulation inferred by curator TFlink
TEAD1 PAX3 21687713 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000034B6F5 PAX3 20956382 rna interference,inhibition experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00001B341F PAX3 19666532 rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS0000330617 PAX3 19666532 rna interference,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay miRSponge
URS000034B6F5 PAX3 20956382 22385659 25416803 25653235 27418678 mrna cleavage,inhibition experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS00001B341F PAX3 19666532 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,miRNA interference luciferase reporter assay TarBase
URS0000330617 PAX3 19666532 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,western blot,miRNA interference luciferase reporter assay TarBase
URS000005481D PAX3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 PAX3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 PAX3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000085F64 PAX3 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 PAX3 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 PAX3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000009C45F PAX3 25416803 27859625 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS00004C5774 PAX3 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 PAX3 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
DAXX PAX3 10393185 11244500 25348397 27898060 N/A physical interaction,in vivo ComPPI,OmniPath
IPO13 PAX3 25348397 N/A physical interaction ComPPI
MEOX2 PAX3 11423130 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
TBP PAX3 25348397 N/A physical interaction ComPPI
SRC PAX3 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
NCK1 PAX3 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SKAP1 PAX3 25348397 N/A physical interaction ComPPI
GRB2 PAX3 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
TAF1 PAX3 21145483 25348397 27898060 N/A physical interaction ComPPI,OmniPath
FZR1 PAX3 25348397 N/A physical interaction ComPPI
CIB1 PAX3 11997098 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
MEOX1 PAX3 11423130 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
SOX8 PAX3 14525934 16582099 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TRIM28 PAX3 25348397 N/A physical interaction ComPPI
RAD23B PAX3 25348397 N/A physical interaction ComPPI
FYN PAX3 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PSMD4 PAX3 25348397 N/A physical interaction ComPPI
PAX3 SOX10 10942418 11029584 12668617 14525934 24234451 25348397 27898060 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
PAX3 WWTR1 14525934 16300735 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PAX3 MSX1 10529415 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
PAX3 HDAC10 25348397 N/A physical interaction ComPPI
PAX3 HDAC1 25348397 N/A physical interaction ComPPI
PAX3 POU3F2 11029584 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
PAX3 PCTP 25348397 N/A physical interaction ComPPI
PAX3 SPIN1 25348397 N/A physical interaction ComPPI
PAX3 FOXE1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PAX3 NELL2 25348397 N/A physical interaction ComPPI
PAX3 ABL1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PAX3 PAX3 10393185 14525934 N/A experimental interaction detection HPRD
MITF PAX3 14525934 15729346 N/A experimental interaction detection HPRD
PAX3 SKI 24234451 26977879 association chromatin immunoprecipitation assay IntAct
PAX3 MDM2 22216266 27898060 N/A N/A OmniPath
PAX3 LEF1 15729346 20006729 27898060 stimulant N/A OmniPath
CSNK2A1 PAX3 18708529 19904978 25821947 27898060 N/A N/A OmniPath
PAX3 DACH2 14695375 27898060 stimulant N/A OmniPath
DACH2 PAX3 14695375 27898060 stimulant N/A OmniPath

Visualization










  Return