GENE：RNF6
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RNF6 |
| FullNmae | ring finger protein 6 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10069 |
| EnsembleID | ENSG00000127870 |
| Uniprot | Q9Y252 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RNF6 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| RNF6 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RNF6 | GO:0003677,GO:0004842,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0006355,GO:0006511,GO:0006511,GO:0016567,GO:0016605,GO:0030424,GO:0030517,GO:0031965,GO:0043231,GO:0044314,GO:0045893,GO:0045893,GO:0046872,GO:0048675,GO:0050681,GO:0060765,GO:0061630,GO:0070936,GO:0085020 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | RNF6 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | RNF6 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | RNF6 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | RNF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | RNF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | RNF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | RNF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | RNF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | RNF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | RNF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | RNF6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000021D7C8 | RNF6 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS00000F31F4 | RNF6 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | RNF6 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000003ABC4 | RNF6 | 20371350 21572407 24398324 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS00001C3AC1 | RNF6 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00004719AB | RNF6 | 20371350 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000204177 | RNF6 | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004CCA62 | RNF6 | 20371350 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | RNF6 | 20371350 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AF715 | RNF6 | 20371350 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000610EFA | RNF6 | 20371350 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E628F | RNF6 | 20371350 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019F055 | RNF6 | 20371350 21572407 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00006DE17B | RNF6 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BCD9C | RNF6 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000272039 | RNF6 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000009262D | RNF6 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D5FFC | RNF6 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001067D1 | RNF6 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000236310 | RNF6 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018C928 | RNF6 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A4ABF | RNF6 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AFAD1 | RNF6 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| UBE2D1 | RNF6 | 25348397 | N/A | physical interaction | ComPPI |
| AR | RNF6 | 19345326 24234451 25348397 | colocalization,association,physical association | anti bait coimmunoprecipitation,physical interaction,chromatin immunoprecipitation assay,confocal microscopy | ComPPI,IntAct |
| LDB1 | RNF6 | 25348397 | N/A | physical interaction | ComPPI |
| ALOX5 | RNF6 | 25348397 | N/A | physical interaction | ComPPI |
| RNF14 | RNF6 | 19345326 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| UBE2H | RNF6 | 19549727 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| BRCA1 | RNF6 | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| ASAH1 | RNF6 | 25348397 | N/A | physical interaction | ComPPI |
| LIMK1 | RNF6 | 16204183 27898060 | N/A | N/A | OmniPath |