Gene Information gene info

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GENE：MYO6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MYO6
FullNmae myosin VI
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7605
EnsembleID ENSG00000196586
Uniprot Q9UM54

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MYO6 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MYO6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MYO6 GO:0000146,GO:0001726,GO:0001726,GO:0003774,GO:0003779,GO:0005515,GO:0005516,GO:0005516,GO:0005524,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005737,GO:0005765,GO:0005768,GO:0005776,GO:0005794,GO:0005829,GO:0005884,GO:0005886,GO:0005902,GO:0005905,GO:0005938,GO:0006886,GO:0006897,GO:0006897,GO:0006897,GO:0007015,GO:0007605,GO:0009410,GO:0015629,GO:0016020,GO:0016461,GO:0030048,GO:0030048,GO:0030050,GO:0030139,GO:0030139,GO:0030175,GO:0030330,GO:0030665,GO:0031410,GO:0031941,GO:0031965,GO:0032587,GO:0042472,GO:0042491,GO:0043531,GO:0045177,GO:0045334,GO:0048471,GO:0048471,GO:0051015,GO:0051015,GO:0051015,GO:0051046,GO:0060001,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MYO6 hsa:4646 path:hsa04814 Motor proteins - Homo sapiens (human)
MYO6 hsa:4646 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
MYO6 hsa:4646 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDH1 MYO6 17664339 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR MYO6 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA3 MYO6 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 MYO6 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MYO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MYO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MYO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MYO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MYO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A MYO6 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000008A99 MYO6 19843160 20353999 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00004F4657 MYO6 20353999 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00004F4657 MYO6 20353999 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000008A99 MYO6 19843160 20353999 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 MYO6 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000338542 MYO6 18668040 22012620 23446348 25416803 27292025 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS000005481D MYO6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD MYO6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000096022 MYO6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000821E0 MYO6 19536157 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr,clip TarBase
URS00001EFBE3 MYO6 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS000050CCE0 MYO6 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS000043D2C1 MYO6 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000008AA34 MYO6 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000118224 MYO6 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002C02E4 MYO6 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000015188E MYO6 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 MYO6 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000013E79D MYO6 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B MYO6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D MYO6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 MYO6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A MYO6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D MYO6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000913AC MYO6 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GIPC1 MYO6 25361965 interaction type N/A PTMCode2
MYO6 GIPC1 25361965 interaction type N/A PTMCode2
DAB2 MYO6 25361965 interaction type N/A PTMCode2
MYO6 DAB2 25361965 interaction type N/A PTMCode2
MYO6 DAB1 25361965 interaction type N/A PTMCode2
DAB1 MYO6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC42 MYO6 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PAK2 MYO6 25348397 N/A physical interaction ComPPI
WBP2 MYO6 25348397 N/A physical interaction ComPPI
PPP1CB MYO6 25348397 N/A physical interaction ComPPI
CALM1 MYO6 25348397 N/A two hybrid,physical interaction,two hybrid fragment pooling approach ComPPI
OPTN MYO6 25348397 N/A physical interaction ComPPI
FBXO34 MYO6 25348397 N/A physical interaction ComPPI
PPP1R3C MYO6 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP1R9A MYO6 25348397 N/A physical interaction ComPPI
PAK1 MYO6 25348397 N/A physical interaction ComPPI
DAB2 MYO6 11906161 11967127 14525934 15837803 16713569 17187061 18429820 19855435 22323290 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,fluorescence microscopy,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
SP1 MYO6 25348397 N/A physical interaction ComPPI
GRB2 MYO6 12577067 24234451 25348397 association pull down ComPPI,IntAct
JUN MYO6 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
FLNA MYO6 25348397 N/A physical interaction ComPPI
ARHGEF12 MYO6 25348397 N/A physical interaction ComPPI
DOCK7 MYO6 25348397 N/A physical interaction ComPPI
UBB MYO6 16499958 24234451 25348397 N/A pull down ComPPI,IntAct
UBC MYO6 25348397 N/A physical interaction ComPPI
NTRK1 MYO6 25348397 N/A physical interaction ComPPI
PICALM MYO6 25348397 N/A physical interaction ComPPI
DAB1 MYO6 25348397 N/A physical interaction ComPPI
ENO1 MYO6 25348397 N/A physical interaction ComPPI
CANX MYO6 24234451 25348397 29568061 association pull down ComPPI,IntAct
APC MYO6 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
CDH1 MYO6 25348397 N/A physical interaction ComPPI
PSMA1 MYO6 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TNFRSF1A MYO6 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CAPZA1 MYO6 25348397 N/A physical interaction ComPPI
HNRNPL MYO6 25348397 N/A physical interaction ComPPI
DCTN1 MYO6 25348397 N/A physical interaction ComPPI
CFTR MYO6 25348397 N/A physical interaction ComPPI
COPB2 MYO6 25348397 N/A physical interaction ComPPI
AP2A2 MYO6 25348397 N/A physical interaction ComPPI
MYO18A MYO6 25348397 N/A physical interaction ComPPI
GIPC1 MYO6 10198040 12857860 14525934 15975910 16819522 16908842 17145710 17187061 17353931 19855435 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
PDHA1 MYO6 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
REPS1 MYO6 25348397 N/A physical interaction ComPPI
REPS2 MYO6 25348397 N/A physical interaction ComPPI
EPRS1 MYO6 25348397 N/A physical interaction ComPPI
CLTC MYO6 25348397 N/A physical interaction ComPPI
ABCE1 MYO6 25348397 N/A physical interaction ComPPI
AP2A1 MYO6 25348397 N/A physical interaction ComPPI
RAD23A MYO6 25348397 N/A physical interaction ComPPI
EPS15 MYO6 25348397 N/A physical interaction ComPPI
TOM1L2 MYO6 23023224 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
AP2B1 MYO6 11967127 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG1 MYO6 12050163 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
CDK2 MYO6 25348397 N/A physical interaction ComPPI
POLR2A MYO6 25348397 N/A physical interaction ComPPI
TMOD2 MYO6 25348397 N/A physical interaction ComPPI
TAX1BP1 MYO6 25348397 N/A physical interaction ComPPI
RIPK3 MYO6 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNFRSF1B MYO6 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RAD23B MYO6 25348397 N/A physical interaction ComPPI
USP11 MYO6 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAK3 MYO6 11517222 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MYO6 ACTA1 14525934 25348397 27898060 9852149 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
MYO6 RNF11 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
MYO6 CYLD 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO6 USP25 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO6 CALCOCO2 25348397 N/A physical interaction ComPPI
MYO6 FBXO25 25348397 N/A physical interaction ComPPI
MYO6 LMTK2 18029400 18429820 19855435 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MYO6 ESR1 21182205 24234451 25348397 association affinity chromatography technology,physical interaction ComPPI,IntAct
MYO6 TOM1 23023224 24234451 25348397 association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
MYO6 PRKN 25348397 N/A physical interaction ComPPI
MYO6 PAN2 25348397 N/A physical interaction ComPPI
MYO6 FBXO6 25348397 N/A physical interaction ComPPI
MYO6 TP53 25348397 N/A physical interaction ComPPI
MYO6 MOV10 25348397 N/A physical interaction ComPPI
MYO6 NXF1 25348397 N/A physical interaction ComPPI
MYO6 ALK 25348397 N/A physical interaction ComPPI
MYO6 DPP9 25348397 N/A physical interaction ComPPI
MYO6 DNAJC2 25348397 N/A physical interaction ComPPI
MYO6 G6PD 25348397 N/A physical interaction ComPPI
MYO6 NHLRC2 25348397 N/A physical interaction ComPPI
MYO6 CAPZA2 25348397 N/A physical interaction ComPPI
MYO6 CLTB 25348397 N/A physical interaction ComPPI
MYO6 DBN1 25348397 N/A physical interaction ComPPI
MYO6 GAK 25348397 N/A physical interaction ComPPI
MYO6 MYH9 25348397 N/A physical interaction ComPPI
MYO6 ACTR2 25348397 N/A physical interaction ComPPI
MYO6 SYNPO 25348397 N/A physical interaction ComPPI
MYO6 GTSE1 25348397 N/A physical interaction ComPPI
MYO6 ANLN 25348397 N/A physical interaction ComPPI
MYO6 MYO5C 25348397 N/A physical interaction ComPPI
MYO6 MYO19 25348397 N/A physical interaction ComPPI
MYO6 RNF126 25348397 N/A physical interaction ComPPI
MYO6 UBXN1 25348397 N/A physical interaction ComPPI
MYO6 SEC16A 25348397 N/A physical interaction ComPPI
MYO6 AP2M1 25348397 N/A physical interaction ComPPI
MYO6 CLINT1 25348397 N/A physical interaction ComPPI
MYO6 PIK3C2A 25348397 N/A physical interaction ComPPI
MYO6 DDB1 25348397 N/A physical interaction ComPPI
MYO6 DCAF1 25348397 N/A physical interaction ComPPI
MYO6 GTPBP4 25348397 N/A physical interaction ComPPI
MYO6 YTHDC2 25348397 N/A physical interaction ComPPI
MYO6 DCTN2 25348397 N/A physical interaction ComPPI
MYO6 POTEI 25348397 N/A physical interaction ComPPI
MYO6 CUEDC1 25348397 N/A physical interaction ComPPI
MYO6 FBXO30 25348397 N/A physical interaction ComPPI
MYO6 ACTBL2 25348397 N/A physical interaction ComPPI
MYO6 GSN 25348397 N/A physical interaction ComPPI
MYO6 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MYO6 DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MYO6 HSD17B10 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MYO6 G3BP1 25348397 N/A physical interaction ComPPI
MYO6 IKBKE 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MYO6 IKBKG 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MYO6 MAP3K3 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MYO6 E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
MYO6 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
MYO6 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MYO6 STING1 24234451 25348397 29251827 association anti bait coimmunoprecipitation ComPPI,IntAct
PLGRKT MYO6 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CALM2 MYO6 14525934 16169070 24234451 physical association two hybrid pooling approach,two hybrid HPRD,IntAct
ESR2 MYO6 21951318 24234451 association anti tag coimmunoprecipitation IntAct
H2BC9 MYO6 24234451 30021884 physical association cross-linking study IntAct
CSTF3 MYO6 24234451 30021884 physical association cross-linking study IntAct
SLC2A1 MYO6 24234451 30021884 physical association cross-linking study IntAct
FUS MYO6 19558455 27898060 N/A N/A OmniPath
PAK3 MYO6 11517222 20068231 27898060 stimulant N/A OmniPath

Visualization










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