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GENE：ADH5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ADH5
FullNmae alcohol dehydrogenase 5 (class III), chi polypeptide
LocusType gene with protein product
Status Approved
HGNC_id HGNC:253
EnsembleID ENSG00000197894
Uniprot P11766

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ADH5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ADH5 GO:0001523,GO:0003016,GO:0004024,GO:0005504,GO:0005739,GO:0005829,GO:0005829,GO:0006069,GO:0008270,GO:0008270,GO:0009055,GO:0010430,GO:0018467,GO:0022900,GO:0032496,GO:0042802,GO:0045777,GO:0046294,GO:0051409,GO:0051775,GO:0051903,GO:0051903,GO:0070062,GO:0106321,GO:0106322

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ADH5 hsa:128 path:hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human)
ADH5 hsa:128 path:hsa00071 Fatty acid degradation - Homo sapiens (human)
ADH5 hsa:128 path:hsa00350 Tyrosine metabolism - Homo sapiens (human)
ADH5 hsa:128 path:hsa00620 Pyruvate metabolism - Homo sapiens (human)
ADH5 hsa:128 path:hsa00830 Retinol metabolism - Homo sapiens (human)
ADH5 hsa:128 path:hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human)
ADH5 hsa:128 path:hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human)
ADH5 hsa:128 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ADH5 hsa:128 path:hsa01200 Carbon metabolism - Homo sapiens (human)
ADH5 hsa:128 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ADH5 SNTA1 15123239 23180781 physical association peptide array InnateDB
APP ADH5 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR ADH5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 ADH5 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ADH5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ADH5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
RARB ADH5 1996113 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SMARCA4 ADH5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ADH5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ADH5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 ADH5 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000600E6 ADH5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000023133F ADH5 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00002EF20A ADH5 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 ADH5 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000075A608 ADH5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF ADH5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004C689A ADH5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D ADH5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 ADH5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD ADH5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000358C16 ADH5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001383CF ADH5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 ADH5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 ADH5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE ADH5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 ADH5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 ADH5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00006DE17B ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000037E170 ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000122ED0 ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000032EF64 ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000237CBD ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000029979D ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000000B1C9 ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000A07C1 ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000031E12 ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000324096 ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB0E ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000032835F ADH5 23313552 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
VTN ADH5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
STIP1 ADH5 25348397 N/A physical interaction ComPPI
PRDX1 ADH5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTPN4 ADH5 25348397 N/A physical interaction ComPPI
TP73 ADH5 25348397 N/A physical interaction ComPPI
SNTA1 ADH5 25348397 N/A physical interaction ComPPI
TP63 ADH5 25348397 N/A physical interaction ComPPI
ESRRA ADH5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CSNK2B ADH5 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ADH5 CHD3 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ADH5 TP53 25348397 N/A physical interaction ComPPI
ADH5 APP 25348397 N/A physical interaction ComPPI
ADH5 HDAC1 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ADH5 ARNT 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ADH5 SLC66A2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ADH5 PHGDH 25348397 N/A physical interaction ComPPI
ADH5 PTGR1 25348397 N/A physical interaction ComPPI
ADH5 ALDH4A1 25348397 N/A physical interaction ComPPI
ESD ADH5 25348397 N/A physical interaction ComPPI
ADH5 ADH5 12196016 14525934 21988832 24234451 physical association two hybrid,experimental interaction detection HPRD,IntAct

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