GENE：ANO1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ANO1 |
| FullNmae | anoctamin 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:21625 |
| EnsembleID | ENSG00000131620 |
| Uniprot | Q5XXA6 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ANO1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ANO1 | GO:0005102,GO:0005227,GO:0005229,GO:0005229,GO:0005229,GO:0005229,GO:0005229,GO:0005247,GO:0005254,GO:0005254,GO:0005515,GO:0005654,GO:0005886,GO:0005886,GO:0005886,GO:0005886,GO:0006812,GO:0006821,GO:0006821,GO:0007200,GO:0015111,GO:0015705,GO:0016324,GO:0034220,GO:0034605,GO:0034707,GO:0035774,GO:0035774,GO:0042802,GO:0042803,GO:0042995,GO:0046872,GO:0050965,GO:0070062,GO:0070254,GO:0070254,GO:0072657,GO:0098655,GO:0098793,GO:0106091,GO:1901653,GO:1902476,GO:1902476,GO:1902476 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | ANO1 | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA1 | ANO1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ANO1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | ANO1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | ANO1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| CEBPA | ANO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ANO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ANO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ANO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ANO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | ANO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | ANO1 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00001FFA8C | ANO1 | 25416803 28193228 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CFTR | ANO1 | 22178883 24234451 25348397 27898060 | colocalization,physical association | anti bait coimmunoprecipitation,fluorescence microscopy | ComPPI,IntAct,OmniPath |
| EWSR1 | ANO1 | 25348397 | N/A | physical interaction | ComPPI |
| H2BC9 | ANO1 | 24234451 30021884 | physical association | cross-linking study | IntAct |