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GENE：BCL9

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BCL9
FullNmae BCL9 transcription coactivator
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1008
EnsembleID ENSG00000116128
Uniprot O00512

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BCL9 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
BCL9 GO:0003713,GO:0005515,GO:0005654,GO:0005801,GO:0006366,GO:0008013,GO:0014908,GO:0016528,GO:0035019,GO:0035914,GO:0045445,GO:0045944,GO:0060070,GO:1990907,GO:1990907,GO:1990907

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BCL9 SMAD1 10391247 11955436 11967263 12051714 15001769 15082531 15576399 16039586 17143292 17936032 19619488 20705860 22290435 22761862 23343194 24023259 25730849 26192618 7542250 8666229 interaction type N/A ACSN
BCL9 TCF4 10391247 11274345 11929833 11955436 11967263 12051714 15001769 15082531 15377999 15576399 15766563 15768032 15806138 16007074 16039586 16169192 16510874 16940750 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19020303 19619488 19623618 19751508 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22270359 22290435 22699938 22705350 22761862 23306204 23343194 24023259 25730849 26192618 26587781 7542250 8545107 8666229 interaction type N/A ACSN
BCL9 KLF8 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20107328 20705860 21151179 21285352 21416054 22290435 22761862 23343194 24023259 25730849 26192618 7542250 8666229 interaction type N/A ACSN
JUN BCL9 10391247 11274345 11929833 11955436 11967263 11973335 12051714 12417340 12711682 15001769 15060161 15082531 15208637 15279786 15327769 15337521 15576399 15768032 15806138 15834423 16007074 16007092 16039586 16169192 16510874 16547505 16554443 16940750 17050667 17143292 17291450 17303408 17306568 17439715 17565603 17660363 17666529 17671186 17936032 18347071 18590585 18627596 19216735 19506021 19619488 19623618 19751508 19751731 19879327 19901072 20006983 20107328 20122174 20144767 20530697 20705860 20920541 20964627 21151179 21285352 21416054 21681822 21767405 22020335 22270359 22290435 22705350 22761862 23296977 23306204 23343194 24023259 25730849 26192618 26587781 7542250 7575488 8545107 8666229 interaction type N/A ACSN
APC BCL9 11274345 11955436 11967263 12051714 12711682 15001769 15327769 15834423 16039586 16510874 16547505 16940750 17143292 17439715 17936032 19216735 19506021 19619488 19623618 19751508 20006983 20705860 20964627 21285352 21681822 22270359 23343194 24023259 25730849 26192618 26587781 7542250 8545107 8666229 interaction type N/A ACSN
BCL9 MYC 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 26192618 7542250 8666229 interaction type N/A ACSN
BCL9 AXIN1 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 26192618 7542250 8666229 interaction type N/A ACSN
BCL9 MMP9 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 26192618 7542250 8666229 interaction type N/A ACSN
KLF4 BCL9 19751731 19901072 26192618 association N/A ACSN
BCL9 IRS2 11274345 11955436 11967263 12051714 12417340 15001769 15279786 15337521 16007092 16039586 16510874 17143292 17303408 17439715 17565603 17660363 17936032 18590585 19619488 19623618 19879327 20006983 20144767 20530697 20705860 20920541 21285352 22020335 23296977 23343194 24023259 25730849 26192618 26587781 7542250 7575488 8545107 8666229 interaction type N/A ACSN
CTNNB1 BCL9 17052462 23180781 physical association gst pull down,isothermal titration calorimetry,x-ray crystallography InnateDB
BCL9 CTNNB1 15294866 17052462 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR BCL9 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 BCL9 19376833 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ESR2 BCL9 19376833 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 BCL9 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 BCL9 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 BCL9 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 BCL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BCL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BCL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 BCL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS BCL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BCL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 BCL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 BCL9 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 BCL9 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000075ABF4 BCL9 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000137EDE BCL9 22024689 25416803 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000065D58 BCL9 24599134 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00002152A8 BCL9 24599134 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000005CF5F BCL9 24599134 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
BCL9 CTNNB1 25361965 interaction type N/A PTMCode2
CTNNB1 BCL9 25361965 interaction type N/A PTMCode2
BCL9 TCF4 25361965 interaction type N/A PTMCode2
TCF4 BCL9 25361965 interaction type N/A PTMCode2
BCL9 CDC73 25361965 interaction type N/A PTMCode2
CDC73 BCL9 25361965 interaction type N/A PTMCode2
BCL9 PYGO2 25361965 interaction type N/A PTMCode2
PYGO2 BCL9 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC73 BCL9 16630820 17113272 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
EWSR1 BCL9 25348397 N/A physical interaction ComPPI
CTNNB1 BCL9 11955446 14525934 15294866 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
WWOX BCL9 25348397 N/A physical interaction ComPPI
TRIM25 BCL9 25348397 N/A physical interaction ComPPI
ELAVL1 BCL9 25348397 N/A physical interaction ComPPI
PYGO1 BCL9 11955446 14525934 14612447 18498752 24234451 25348397 physical association two hybrid,experimental interaction detection,molecular sieving,pull down,x-ray crystallography,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
BCL9 PYGO2 11955446 14525934 14612447 17113272 21399610 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
BCL9 TCF4 11955446 24234451 25348397 physical association pull down ComPPI,IntAct
ARM BCL9 11955446 17113272 24234451 physical association two hybrid IntAct
PYGO BCL9 11955446 24234451 physical association two hybrid IntAct
BCL9 CTNNB1 11955446 15208637 15294866 1705246 17052462 27898060 stimulant N/A OmniPath
BCL9 PYGO1 11955446 14612447 18498752 27898060 stimulant N/A OmniPath

Visualization










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