GENE：C4BPA
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | C4BPA |
| FullNmae | complement component 4 binding protein alpha |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1325 |
| EnsembleID | ENSG00000123838 |
| Uniprot | P04003 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| C4BPA | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| C4BPA | GO:0002456,GO:0003723,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0005615,GO:0005886,GO:0005886,GO:0006958,GO:0009609,GO:0045087,GO:0045732,GO:0045959,GO:0045959,GO:0072562,GO:1903027 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| C4BPA | hsa:722 | path:hsa04610 | Complement and coagulation cascades - Homo sapiens (human) |
| C4BPA | hsa:722 | path:hsa05133 | Pertussis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | C4BPA | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | C4BPA | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA2 | C4BPA | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | C4BPA | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | C4BPA | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| CEBPA | C4BPA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | C4BPA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| C4BPA | PROS1 | 25361965 | interaction type | N/A | PTMCode2 |
| PROS1 | C4BPA | 25361965 | interaction type | N/A | PTMCode2 |
| C4BPA | C4B | 25361965 | interaction type | N/A | PTMCode2 |
| C4B | C4BPA | 25361965 | interaction type | N/A | PTMCode2 |
| APCS | C4BPA | 25361965 | interaction type | N/A | PTMCode2 |
| C4BPA | APCS | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TSNAX | C4BPA | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SMARCD1 | C4BPA | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| GTF2I | C4BPA | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| PROS1 | C4BPA | 10744423 14525934 1534488 1833851 25348397 27898060 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| LRP1 | C4BPA | 11705989 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| C4BPA | BMPR2 | 14525934 15188402 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| C4BPA | APCS | 12100475 14525934 25348397 27898060 7592941 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
| C4BPA | FN1 | 25348397 | N/A | physical interaction | ComPPI |
| C4BPA | FXYD6 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| C4BPA | LBP | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| C4BPA | GIT2 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| C4BPA | MYH11 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| C4BPA | SEC16A | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| C4BPA | ARMC6 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| C4A | C4BPA | 12893820 14525934 | N/A | experimental interaction detection | HPRD |
| NCBP2 | C4BPA | 24234451 26382858 | association | pull down | IntAct |
| C4BPA | CD40 | 12818164 27898060 | N/A | N/A | OmniPath |