Gene Information gene info

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GENE：CLDN2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CLDN2
FullNmae claudin 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2041
EnsembleID ENSG00000165376
Uniprot P57739

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CLDN2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CLDN2 GO:0005198,GO:0005515,GO:0005886,GO:0005911,GO:0005923,GO:0005923,GO:0016338,GO:0016338,GO:0042802,GO:0070830,GO:0098609

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CLDN2 hsa:9075 path:hsa04514 Cell adhesion molecules - Homo sapiens (human)
CLDN2 hsa:9075 path:hsa04530 Tight junction - Homo sapiens (human)
CLDN2 hsa:9075 path:hsa04670 Leukocyte transendothelial migration - Homo sapiens (human)
CLDN2 hsa:9075 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
CLDN2 hsa:9075 path:hsa05160 Hepatitis C - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR CLDN2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CLDN2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CLDN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CLDN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 CLDN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CLDN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTNNB1 CLDN2 14751232 trascriptional regulation,stimulation inferred by curator TFlink
LEF1 CLDN2 14751232 trascriptional regulation,stimulation inferred by curator TFlink
PPARG CLDN2 16688762 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
PIAS2 CLDN2 25348397 N/A physical interaction ComPPI
UBE2I CLDN2 25348397 N/A physical interaction ComPPI
KRTAP4-12 CLDN2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
LAT CLDN2 25348397 N/A two hybrid ComPPI
CXCL9 CLDN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT31 CLDN2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CLDN2 WNK4 14525934 15070779 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CLDN2 TJP1 10601346 14525934 22546605 24234451 25348397 colocalization experimental interaction detection,physical interaction,confocal microscopy ComPPI,HPRD,IntAct
CLDN2 TJP2 25348397 N/A physical interaction ComPPI
CLDN2 LNX1 25348397 N/A physical interaction ComPPI
CLDN2 KRTAP10-3 25348397 N/A physical interaction ComPPI
CLDN2 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CLDN2 LPAR3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CLDN2 GRM2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CLDN2 IL27RA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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