Gene Information gene info

  1. Home

GENE：COL1A2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol COL1A2
FullNmae collagen type I alpha 2 chain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2198
EnsembleID ENSG00000164692
Uniprot P08123

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
COL1A2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
COL1A2 GO:0001501,GO:0001568,GO:0002020,GO:0005201,GO:0005515,GO:0005576,GO:0005576,GO:0005584,GO:0005584,GO:0005584,GO:0005584,GO:0005584,GO:0005615,GO:0005615,GO:0005788,GO:0007179,GO:0007266,GO:0008217,GO:0030020,GO:0030020,GO:0030020,GO:0030198,GO:0030199,GO:0030199,GO:0030282,GO:0030674,GO:0032963,GO:0042476,GO:0042802,GO:0043589,GO:0046332,GO:0046872,GO:0048407,GO:0062023,GO:0062023,GO:0070062,GO:0070208,GO:0071230,GO:0085029

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
COL1A2 hsa:1278 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
COL1A2 hsa:1278 path:hsa04510 Focal adhesion - Homo sapiens (human)
COL1A2 hsa:1278 path:hsa04512 ECM-receptor interaction - Homo sapiens (human)
COL1A2 hsa:1278 path:hsa04611 Platelet activation - Homo sapiens (human)
COL1A2 hsa:1278 path:hsa04926 Relaxin signaling pathway - Homo sapiens (human)
COL1A2 hsa:1278 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
COL1A2 hsa:1278 path:hsa04974 Protein digestion and absorption - Homo sapiens (human)
COL1A2 hsa:1278 path:hsa05146 Amoebiasis - Homo sapiens (human)
COL1A2 hsa:1278 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
COL1A2 hsa:1278 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
COL1A2 hsa:1278 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
COL1A2 IRF1 16091368 23180781 physical association anti tag coimmunoprecipitation InnateDB
COL1A2 IRF2 16091368 23180781 physical association anti tag coimmunoprecipitation InnateDB
GATA4 COL1A2 16091368 23180781 physical association anti tag coimmunoprecipitation InnateDB
COL1A2 RFX5 19465385 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB
COL1A2 HDAC2 19465385 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB
COL1A2 RFXANK 19465385 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR COL1A2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 COL1A2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 COL1A2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
NFKB1 COL1A2 10201951 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
YBX1 COL1A2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
RELA COL1A2 10201951 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
RFX1 COL1A2 16464847 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
RFX5 COL1A2 16464847 23079621 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 COL1A2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SP1 COL1A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFIC COL1A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TBP COL1A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 COL1A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA COL1A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF COL1A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 COL1A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 COL1A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS COL1A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A COL1A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 COL1A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 COL1A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPZ COL1A2 8910550 trascriptional regulation,stimulation inferred by curator TFlink
CIITA COL1A2 15247294 16439692 trascriptional regulation,stimulation inferred by curator TFlink
EP300 COL1A2 24058639 trascriptional regulation,stimulation inferred by curator TFlink
FLI1 COL1A2 24058639 trascriptional regulation,stimulation inferred by curator TFlink
HDAC1 COL1A2 16464847 24058639 trascriptional regulation,stimulation inferred by curator TFlink
HDAC2 COL1A2 16464847 trascriptional regulation,stimulation inferred by curator TFlink
KLF11 COL1A2 24069400 trascriptional regulation,stimulation inferred by curator TFlink
MYB COL1A2 9989795 trascriptional regulation,stimulation inferred by curator TFlink
SIRT1 COL1A2 23079621 trascriptional regulation,stimulation inferred by curator TFlink
STAT6 COL1A2 14603527 trascriptional regulation,stimulation inferred by curator TFlink
YY1 COL1A2 8910550 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000029979D COL1A2 20338660 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000272A3D COL1A2 N/A 18390668 \N rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS0000272A3D COL1A2 18390668 18927107 21125666 24590289 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS000029979D COL1A2 20338660 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000BD6DC COL1A2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F COL1A2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C COL1A2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004E02F2 COL1A2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE COL1A2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A COL1A2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA COL1A2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 COL1A2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F COL1A2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 COL1A2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000913AC COL1A2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 COL1A2 25416803 28079129 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000C85B2 COL1A2 25416803 28059478 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr TarBase
URS0000076995 COL1A2 25416803 26794609 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
VWF COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 VWF 25361965 interaction type N/A PTMCode2
DCN COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 DCN 25361965 interaction type N/A PTMCode2
ITGA2 COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 ITGA2 25361965 interaction type N/A PTMCode2
COL1A2 CD36 25361965 interaction type N/A PTMCode2
CD36 COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 BGN 25361965 interaction type N/A PTMCode2
BGN COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 MMP9 25361965 interaction type N/A PTMCode2
MMP9 COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 SHBG 25361965 interaction type N/A PTMCode2
SHBG COL1A2 25361965 interaction type N/A PTMCode2
RFX1 COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 RFX1 25361965 interaction type N/A PTMCode2
SPARC COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 SPARC 25361965 interaction type N/A PTMCode2
ITGB3 COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 ITGB3 25361965 interaction type N/A PTMCode2
ITGA2B COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 ITGA2B 25361965 interaction type N/A PTMCode2
APP COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 APP 25361965 interaction type N/A PTMCode2
COL1A1 COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 COL1A1 25361965 interaction type N/A PTMCode2
LUM COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 LUM 25361965 interaction type N/A PTMCode2
CD44 COL1A2 25361965 interaction type N/A PTMCode2
COL1A2 CD44 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SGTA COL1A2 24234451 25348397 25416956 26871637 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
COL1A2 SHBG 14525934 15862967 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
COL1A2 COL5A3 10722718 14525934 25348397 6501291 7346227 N/A experimental interaction detection,in vivo ComPPI,HPRD
COL1A2 MMP9 14525934 25348397 9878537 N/A experimental interaction detection,protease assay,in vivo ComPPI,HPRD
COL1A2 CD93 1377218 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
COL1A2 ITGB3 14525934 1693626 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
COL1A2 CD36 10772928 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
COL1A2 SPARC 14525934 25348397 7034958 N/A experimental interaction detection,in vitro ComPPI,HPRD
COL1A2 ITGA2 14525934 17485091 2156854 24234451 25348397 N/A experimental interaction detection,biochemical,in vitro ComPPI,HPRD,IntAct
COL1A2 VWF 14525934 25348397 3490481 N/A experimental interaction detection,in vitro ComPPI,HPRD
COL1A2 BGN 14525934 25348397 7852349 N/A experimental interaction detection,in vitro ComPPI,HPRD
COL1A2 LUM 10734230 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
COL1A2 TGFBI 11867580 12034705 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
COL1A2 ITGA2B 11359786 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
COL1A2 P4HB 10329688 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
COL1A2 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
COL1A2 CD44 14525934 1730778 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
COL1A2 MMP1 25348397 N/A protease assay ComPPI
COL1A2 MMP2 25348397 N/A protease assay ComPPI
COL1A2 MMP3 25348397 N/A protease assay ComPPI
COL1A2 COL5A1 20979576 24234451 25348397 physical association two hybrid ComPPI,IntAct
COL1A2 MMP8 25348397 N/A protease assay ComPPI
COL1A2 LOX 21690299 24234451 25348397 physical association two hybrid ComPPI,IntAct
COL1A2 CTSK 25348397 N/A protease assay ComPPI
COL1A2 MMP14 25348397 N/A protease assay ComPPI
COL1A2 MMP15 25348397 N/A protease assay ComPPI
COL1A2 MMP16 25348397 N/A protease assay ComPPI
COL1A2 DDR1 25348397 N/A enzyme linked immunosorbent assay ComPPI
COL1A2 LIG4 25348397 N/A physical interaction ComPPI
COL1A2 PAN2 25348397 N/A physical interaction ComPPI
COL1A2 COL1A1 25348397 N/A physical interaction ComPPI
COL1A2 PDGFA 25348397 N/A physical interaction ComPPI
COL1A2 PDGFB 25348397 N/A physical interaction ComPPI
COL1A2 UBQLN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
COL1A2 ERAL1 25348397 N/A physical interaction ComPPI
COL1A2 CAMKMT 25348397 N/A physical interaction ComPPI
COL1A2 COMT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL1A2 RAB5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL1A2 ZWINT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL1A2 CDKN2AIP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL1A2 SERPINB5 25348397 N/A physical interaction ComPPI
COL1A2 EGFR 25348397 N/A physical interaction ComPPI
COL1A2 SBF1 25348397 N/A physical interaction ComPPI
COL1A2 YAF2 25348397 N/A physical interaction ComPPI
COL1A2 TIMM44 25348397 N/A physical interaction ComPPI
COL1A2 CYLD 25348397 N/A physical interaction ComPPI
COL1A2 HTN3 25348397 N/A physical interaction ComPPI
COL1A2 ZNF16 21874239 24234451 25348397 physical association two hybrid ComPPI,IntAct
COL1A2 TFAP2C 24234451 24835590 25348397 physical association two hybrid ComPPI,IntAct
COL1A2 KCNIP4 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
COL1A2 SGTB 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
COL1A2 MESD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COL1A2 EIF3F 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COL1A2 SMARCD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COL1A2 UBQLN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DCN COL1A2 14525934 1468447 2375748 27898060 9675033 N/A experimental interaction detection HPRD,OmniPath
FN1 COL1A2 14525934 8468356 N/A experimental interaction detection HPRD
COL1A2 APP 14525934 27898060 7688497 N/A experimental interaction detection HPRD,OmniPath
MYB COL1A2 27898060 9989795 stimulant N/A OmniPath

Visualization










  Return