Gene Information gene info

GENE:CXXC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CXXC1
FullNmae CXXC finger protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24343
EnsembleID ENSG00000154832
Uniprot Q9P0U4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CXXC1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CXXC1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CXXC1 GO:0000987,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006355,GO:0008270,GO:0016363,GO:0016607,GO:0035064,GO:0035064,GO:0035097,GO:0045322,GO:0045893,GO:0045893,GO:0048188,GO:0048188,GO:0048188

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 CXXC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CXXC1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC CXXC1 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 CXXC1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 CXXC1 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CXXC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CXXC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CXXC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CXXC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 CXXC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000005481D CXXC1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ASH2L CXXC1 25361965 interaction type N/A PTMCode2
CXXC1 ASH2L 25361965 interaction type N/A PTMCode2
RBBP5 CXXC1 25361965 interaction type N/A PTMCode2
CXXC1 RBBP5 25361965 interaction type N/A PTMCode2
WDR5 CXXC1 25361965 interaction type N/A PTMCode2
CXXC1 WDR5 25361965 interaction type N/A PTMCode2
SETD1A CXXC1 25361965 interaction type N/A PTMCode2
CXXC1 SETD1A 25361965 interaction type N/A PTMCode2
MEN1 CXXC1 25361965 interaction type N/A PTMCode2
CXXC1 MEN1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ZNF408 CXXC1 25348397 N/A physical interaction ComPPI
DPY30 CXXC1 23870121 23995757 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMC3 CXXC1 25348397 N/A physical interaction ComPPI
MEOX2 CXXC1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NR5A1 CXXC1 25348397 N/A physical interaction ComPPI
HSP90AB1 CXXC1 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
H4C1 CXXC1 25348397 N/A physical interaction ComPPI
TBP CXXC1 16713569 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HCFC1 CXXC1 23870121 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EP300 CXXC1 23870121 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSP90AA1 CXXC1 25348397 N/A physical interaction ComPPI
KMT2D CXXC1 25348397 N/A physical interaction ComPPI
ASH2L CXXC1 23870121 24234451 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP1CA CXXC1 22321011 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDK CXXC1 25348397 N/A physical interaction ComPPI
RBBP5 CXXC1 23870121 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRMT2 CXXC1 25348397 N/A physical interaction ComPPI
CAMK2D CXXC1 25348397 N/A physical interaction ComPPI
WDR77 CXXC1 25348397 N/A physical interaction ComPPI
H3C15 CXXC1 25348397 N/A physical interaction ComPPI
RNF2 CXXC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OGT CXXC1 23353889 24234451 25348397 27705803 association pull down,tandem affinity purification ComPPI,IntAct
TAX1BP1 CXXC1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EDA CXXC1 25348397 N/A physical interaction ComPPI
PRPS1 CXXC1 25348397 N/A physical interaction ComPPI
SMURF1 CXXC1 25348397 N/A in vivo ComPPI
NUP50 CXXC1 25348397 N/A physical interaction ComPPI
H2AX CXXC1 25348397 N/A physical interaction ComPPI
PES1 CXXC1 25348397 N/A physical interaction ComPPI
CXXC1 SETD1A 16253997 17355966 17998332 18082152 18680430 19410543 19433449 19951360 23453808 23870121 24234451 25348397 26496610 27898060 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
CXXC1 KMT2A 25348397 N/A physical interaction ComPPI
CXXC1 SETD1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CXXC1 WDR82 23870121 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CXXC1 KIFC1 25348397 N/A physical interaction ComPPI
CXXC1 MEN1 25348397 N/A physical interaction ComPPI
CXXC1 DNMT1 25348397 N/A physical interaction ComPPI
CXXC1 HSP90AA2P 25348397 N/A physical interaction ComPPI
CXXC1 TP53 23870121 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cross-linking study,pull down,physical interaction ComPPI,IntAct
CXXC1 KRT75 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CXXC1 BOD1L1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CXXC1 BOD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CXXC1 HCFC2 25348397 N/A physical interaction ComPPI
CXXC1 EPB41L5 25348397 N/A physical interaction ComPPI
CXXC1 PIP4K2A 25348397 N/A physical interaction ComPPI
CXXC1 RSBN1 25348397 N/A physical interaction ComPPI
WDR5 CXXC1 23870121 24234451 25348397 26496610 27705803 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
MKI67 CXXC1 24234451 26949251 association anti tag coimmunoprecipitation IntAct

Visualization