Gene Information gene info

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GENE：DDX21

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DDX21
FullNmae DExD-box helicase 21
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2744
EnsembleID ENSG00000165732
Uniprot Q9NR30

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DDX21 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DDX21 GO:0001649,GO:0002735,GO:0003723,GO:0003723,GO:0003724,GO:0003724,GO:0003724,GO:0003725,GO:0005515,GO:0005524,GO:0005654,GO:0005654,GO:0005694,GO:0005730,GO:0005730,GO:0005730,GO:0005739,GO:0005829,GO:0006338,GO:0006364,GO:0006366,GO:0016020,GO:0016479,GO:0016887,GO:0019843,GO:0030515,GO:0035066,GO:0035198,GO:0042802,GO:0043123,GO:0043330,GO:0045087,GO:0045943,GO:0045944,GO:0045945,GO:0051607,GO:0062176,GO:0097322,GO:0110016,GO:0140870

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YWHAE DDX21 20462248 23180781 physical association anti tag coimmunoprecipitation InnateDB
EED DDX21 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 DDX21 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 DDX21 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DDX21 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A DDX21 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 DDX21 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DDX21 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DDX21 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DDX21 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DDX21 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN DDX21 22550165 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 DDX21 21512034 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000272A3D DDX21 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000EED18 DDX21 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000324096 DDX21 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000070B1D DDX21 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 DDX21 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC DDX21 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 DDX21 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 DDX21 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A405B DDX21 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000007FBA DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000498DAA DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000015F70F DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 DDX21 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DDX21 SRPK1 25361965 interaction type N/A PTMCode2
SRPK1 DDX21 25361965 interaction type N/A PTMCode2
SSRP1 DDX21 25361965 interaction type N/A PTMCode2
DDX21 SSRP1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I DDX21 25348397 N/A physical interaction ComPPI
SNW1 DDX21 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CDC5L DDX21 25348397 N/A physical interaction ComPPI
HNRNPC DDX21 15034300 24234451 25348397 30021884 physical association cross-linking study,chromatography technology ComPPI,IntAct
SAP18 DDX21 25348397 N/A physical interaction ComPPI
KPNA3 DDX21 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DDX21 JUN 11823437 14525934 24234451 25348397 25609649 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
DDX21 PIAS1 14525934 25348397 27898060 9177271 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
DDX21 LYAR 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 PSTPIP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 RTCA 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 SMNDC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
DDX21 SRRM2 25348397 N/A physical interaction ComPPI
DDX21 SRRM1 25348397 N/A physical interaction ComPPI
DDX21 CTNNBL1 25348397 N/A physical interaction ComPPI
DDX21 DOT1L 25348397 N/A physical interaction ComPPI
DDX21 NPM1 25348397 N/A physical interaction ComPPI
DDX21 NOP56 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 TOP1 15848144 24234451 25348397 association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
DDX21 CALM1 25348397 N/A physical interaction ComPPI
DDX21 PCK1 25348397 N/A physical interaction ComPPI
DDX21 HDGF 21907836 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DDX21 SIRT7 25348397 N/A physical interaction ComPPI
DDX21 HNRNPA1 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
DDX21 TERF1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
DDX21 TERF2 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
DDX21 CUL3 25348397 N/A physical interaction ComPPI
DDX21 CUL4A 25348397 N/A physical interaction ComPPI
DDX21 CDK2 25348397 N/A physical interaction ComPPI
DDX21 GRK5 25348397 N/A physical interaction ComPPI
DDX21 RPL6 25348397 N/A physical interaction ComPPI
DDX21 RPL7 25348397 N/A physical interaction ComPPI
DDX21 RPL31 25348397 N/A physical interaction ComPPI
DDX21 RPL37A 25348397 N/A physical interaction ComPPI
DDX21 RPS11 25348397 N/A physical interaction ComPPI
DDX21 RPS24 25348397 N/A physical interaction ComPPI
DDX21 RPL5 25348397 N/A physical interaction ComPPI
DDX21 RSL1D1 25348397 N/A physical interaction ComPPI
DDX21 RPL19 25348397 N/A physical interaction ComPPI
DDX21 RPS23 25348397 N/A physical interaction ComPPI
DDX21 IK 25348397 N/A physical interaction ComPPI
DDX21 RNPS1 25348397 N/A physical interaction ComPPI
DDX21 SRSF5 25348397 N/A physical interaction ComPPI
DDX21 SRSF7 25348397 N/A physical interaction ComPPI
DDX21 HNRNPR 25348397 N/A physical interaction ComPPI
DDX21 SFPQ 25348397 N/A physical interaction ComPPI
DDX21 EFTUD2 25348397 N/A physical interaction ComPPI
DDX21 RBM39 25348397 N/A physical interaction ComPPI
DDX21 PARP1 25348397 N/A physical interaction ComPPI
DDX21 RRP7A 25348397 N/A physical interaction ComPPI
DDX21 RRS1 25348397 N/A physical interaction ComPPI
DDX21 THRAP3 25348397 N/A physical interaction ComPPI
DDX21 SON 25348397 N/A physical interaction ComPPI
DDX21 MYO1C 25348397 N/A physical interaction ComPPI
DDX21 SSR3 25348397 N/A physical interaction ComPPI
DDX21 FTSJ3 25348397 N/A physical interaction ComPPI
DDX21 NFIA 25348397 N/A physical interaction ComPPI
DDX21 NOP2 25348397 N/A physical interaction ComPPI
DDX21 SMARCA1 25348397 N/A physical interaction ComPPI
DDX21 PCDHA2 25348397 N/A physical interaction ComPPI
DDX21 SUPT16H 25348397 N/A physical interaction ComPPI
DDX21 PDS5A 25348397 N/A physical interaction ComPPI
DDX21 LAMP2 25348397 N/A physical interaction ComPPI
DDX21 LMNB1 25348397 N/A physical interaction ComPPI
DDX21 S100A9 25348397 N/A physical interaction ComPPI
DDX21 ESR1 21182205 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
DDX21 APTX 25348397 N/A physical interaction ComPPI
DDX21 H2AX 25348397 N/A physical interaction ComPPI
DDX21 SMURF1 25348397 N/A physical interaction ComPPI
DDX21 YWHAE 25348397 N/A physical interaction ComPPI
DDX21 VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
DDX21 FN1 25348397 N/A physical interaction ComPPI
DDX21 CSNK2A1 25348397 N/A physical interaction,protein kinase assay ComPPI
DDX21 IL7R 25348397 N/A physical interaction ComPPI
DDX21 ITGA4 25348397 N/A physical interaction ComPPI
DDX21 AICDA 25348397 N/A physical interaction ComPPI
DDX21 PAN2 25348397 N/A physical interaction ComPPI
DDX21 LYN 25348397 N/A physical interaction ComPPI
DDX21 SRPK2 23602568 24234451 25348397 association,physical association physical interaction,tandem affinity purification,bimolecular fluorescence complementation ComPPI,IntAct
DDX21 SRPK3 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DDX21 FBXO6 25348397 N/A physical interaction ComPPI
DDX21 TARDBP 25348397 N/A physical interaction ComPPI
DDX21 WWOX 25348397 N/A physical interaction ComPPI
DDX21 ERG 25348397 N/A physical interaction ComPPI
DDX21 LGR4 25348397 N/A physical interaction ComPPI
DDX21 IVNS1ABP 25348397 N/A physical interaction ComPPI
DDX21 STAU1 25348397 N/A physical interaction ComPPI
DDX21 CEP250 25348397 N/A physical interaction ComPPI
DDX21 HUWE1 25348397 N/A physical interaction ComPPI
DDX21 PA2G4 25348397 N/A physical interaction ComPPI
DDX21 CUL7 25348397 N/A physical interaction ComPPI
DDX21 OBSL1 25348397 N/A physical interaction ComPPI
DDX21 CCDC8 25348397 N/A physical interaction ComPPI
DDX21 EED 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 SUMO2 25348397 N/A physical interaction ComPPI
DDX21 ILK 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 MAST3 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 LUZP4 25348397 N/A physical interaction ComPPI
DDX21 EBNA1BP2 25348397 N/A physical interaction ComPPI
DDX21 RPL14 25348397 N/A physical interaction ComPPI
DDX21 ZC3H3 25348397 N/A physical interaction ComPPI
DDX21 THUMPD1 25348397 N/A physical interaction ComPPI
DDX21 NTRK1 25348397 N/A physical interaction ComPPI
DDX21 DDX50 25348397 N/A physical interaction ComPPI
DDX21 H3C1 25348397 N/A physical interaction ComPPI
DDX21 HNRNPU 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 RPL10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 IBTK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 MACROD1 25348397 N/A physical interaction ComPPI
DDX21 MCM2 25348397 N/A physical interaction ComPPI
DDX21 MCM5 25348397 N/A physical interaction ComPPI
DDX21 U2AF2 25348397 N/A physical interaction ComPPI
DDX21 C1ORF131 25348397 N/A physical interaction ComPPI
DDX21 ZNF746 25348397 N/A physical interaction ComPPI
DDX21 RBM34 25348397 N/A physical interaction ComPPI
DDX21 FGF8 25348397 N/A physical interaction ComPPI
DDX21 WDR46 25348397 N/A physical interaction ComPPI
DDX21 H1-6 25348397 N/A physical interaction ComPPI
DDX21 SYNCRIP 25348397 N/A physical interaction ComPPI
DDX21 ZNF512 25348397 N/A physical interaction ComPPI
DDX21 RPL30 25348397 N/A physical interaction ComPPI
DDX21 CNBP 25348397 N/A physical interaction ComPPI
DDX21 MACROH2A2 25348397 N/A physical interaction ComPPI
DDX21 MECP2 25348397 N/A physical interaction ComPPI
DDX21 E4F1 25348397 N/A physical interaction ComPPI
DDX21 ZCRB1 25348397 N/A physical interaction ComPPI
DDX21 RBM4 25348397 N/A physical interaction ComPPI
DDX21 FGF3 25348397 N/A physical interaction ComPPI
DDX21 NIFK 25348397 N/A physical interaction ComPPI
DDX21 NCL 25348397 N/A physical interaction ComPPI
DDX21 INO80B 25348397 N/A physical interaction ComPPI
DDX21 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DDX21 DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DDX21 DNM1L 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DDX21 VDAC1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
DDX21 G3BP1 25348397 N/A physical interaction ComPPI
DDX21 BRCA1 25348397 N/A physical interaction ComPPI
DDX21 LMNA 25348397 N/A physical interaction ComPPI
DDX21 RNF168 25348397 N/A physical interaction ComPPI
DDX21 TES 25348397 N/A physical interaction ComPPI
DDX21 MTF1 25348397 N/A physical interaction ComPPI
DDX21 KEAP1 25348397 N/A physical interaction ComPPI
DDX21 XRN2 24234451 25348397 25470060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 LARP7 24234451 25348397 25470060 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 CDK9 24234451 25348397 25470060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 NOP58 24234451 25348397 25470060 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 DKC1 24234451 25348397 25470060 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 FBL 24234451 25348397 25470060 29568061 association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DDX21 HEXIM1 24234451 25348397 25470060 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 NFKB2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
DDX21 MAP3K14 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
DDX21 RELA 25348397 N/A tandem affinity purification ComPPI
DDX21 MED19 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX21 DHX9 15034300 24234451 25348397 physical association chromatography technology ComPPI,IntAct
DDX21 PRPF8 15034300 24234451 25348397 physical association chromatography technology ComPPI,IntAct
DDX21 SRPK1 15034300 24234451 25348397 physical association chromatography technology ComPPI,IntAct
DDX21 SSRP1 15034300 24234451 25348397 physical association chromatography technology ComPPI,IntAct
DDX21 TOP2A 15034300 24234451 25348397 physical association chromatography technology ComPPI,IntAct
DDX21 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DDX21 PINX1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DDX21 CDC42BPB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DDX21 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DDX21 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DDX21 GH1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DDX21 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DDX21 PPP2R2B 25348397 N/A pull down ComPPI
DDX21 GABARAPL2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX21 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX21 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX21 E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
DDX21 MEX3C 22863774 24234451 25348397 association pull down ComPPI,IntAct
DDX21 MCM7 23764002 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
DDX21 YBX1 23986595 24234451 25348397 25497084 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
DDX21 MNDA 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX21 NFKB1 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
DDX21 DUX4 24234451 25348397 26816005 association pull down ComPPI,IntAct
DDX21 HSCB 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
DDX21 ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX21 RPS6 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRAF6 DDX21 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
METTL14 DDX21 24234451 29507755 association anti tag coimmunoprecipitation IntAct
VDAC2 DDX21 24234451 30021884 physical association cross-linking study IntAct
DDX21 TAAR3P 24234451 30021884 physical association cross-linking study IntAct
DDX21 NCF2 24234451 30021884 physical association cross-linking study IntAct
DDX21 DOCK3 24234451 30021884 physical association cross-linking study IntAct
DDX21 ZC3H7B 24234451 30021884 physical association cross-linking study IntAct
DDX21 FBXO44 24234451 30021884 physical association cross-linking study IntAct
DDX21 EPSTI1 24234451 30021884 physical association cross-linking study IntAct
DDX21 DISP3 24234451 30021884 physical association cross-linking study IntAct
SPTAN1 DDX21 24234451 30021884 physical association cross-linking study IntAct
H1-2 DDX21 24234451 30021884 physical association cross-linking study IntAct
L1TD1 DDX21 24234451 25702638 association anti bait coimmunoprecipitation IntAct

Visualization










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