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GENE：DIXDC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DIXDC1
FullNmae DIX domain containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23695
EnsembleID ENSG00000150764
Uniprot Q155Q3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DIXDC1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DIXDC1 GO:0003779,GO:0005515,GO:0005829,GO:0005829,GO:0005856,GO:0005925,GO:0019904,GO:0021799,GO:0021869,GO:0030177,GO:0032956,GO:0043015,GO:0045665,GO:0060070,GO:0060070,GO:0070507

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DIXDC1 DVL1 21189423 interaction type,stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR DIXDC1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 DIXDC1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 DIXDC1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 DIXDC1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 DIXDC1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 DIXDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DIXDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DIXDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DIXDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DIXDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DIXDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DIXDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DIXDC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 DIXDC1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000B0E50 DIXDC1 23295946 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
MARK1 DIXDC1 22135298 phosphorylation N/A PhosphoSite
AXIN1 DIXDC1 25361965 interaction type N/A PTMCode2
DIXDC1 AXIN1 25361965 interaction type N/A PTMCode2
MAP3K4 DIXDC1 25361965 interaction type N/A PTMCode2
DIXDC1 MAP3K4 25361965 interaction type N/A PTMCode2
NDEL1 DIXDC1 25361965 interaction type N/A PTMCode2
DIXDC1 NDEL1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC5L DIXDC1 25348397 N/A physical interaction ComPPI
ATXN1 DIXDC1 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
FLNA DIXDC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AXIN1 DIXDC1 14525934 15262978 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PLK1 DIXDC1 20823832 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MAP3K4 DIXDC1 14525934 15262978 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PKM DIXDC1 25348397 N/A protein kinase assay ComPPI
DVL2 DIXDC1 20823832 24234451 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
ZDHHC17 DIXDC1 25348397 N/A physical interaction ComPPI
EGFR DIXDC1 25348397 N/A physical interaction ComPPI
NDEL1 DIXDC1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DIXDC1 APP 25348397 N/A physical interaction ComPPI
DIXDC1 ULK2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DIXDC1 L3HYPDH 25348397 N/A physical interaction ComPPI
DIXDC1 CAPZA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DIXDC1 DBN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DIXDC1 MYH9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DIXDC1 MYO1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

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