Gene Information gene info

  1. Home

GENE：EFNA2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EFNA2
FullNmae ephrin A2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3222
EnsembleID ENSG00000099617
Uniprot O43921

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EFNA2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EFNA2 GO:0005515,GO:0005886,GO:0005886,GO:0007267,GO:0007411,GO:0021772,GO:0030316,GO:0030316,GO:0031594,GO:0043204,GO:0046849,GO:0046849,GO:0046875,GO:0048013,GO:0048013,GO:0098552

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EFNA2 hsa:1943 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
EFNA2 hsa:1943 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
EFNA2 hsa:1943 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
EFNA2 hsa:1943 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
EFNA2 hsa:1943 path:hsa04360 Axon guidance - Homo sapiens (human)
EFNA2 hsa:1943 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EFNA2 KIR3DL1 16818466 23180781 physical association electrophoretic mobility supershift assay InnateDB
EFNA2 EPHA2 18988627 23331499 8755474 9267020 stimulation N/A SignaLink,SignaLink
EFNA2 EPHA6 23331499 9576626 stimulation N/A SignaLink,SignaLink
EFNA2 EPHA7 23331499 9576626 stimulation N/A SignaLink
EFNA2 EPHA8 23331499 9576626 stimulation N/A SignaLink
EFNA2 EPHA5 10531456 23331499 9576626 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
TP53 EFNA2 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
EGR1 EFNA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EFNA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 EFNA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 EFNA2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 EFNA2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000075994C EFNA2 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000012930C EFNA2 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000AD02D EFNA2 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000E601 EFNA2 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EFNA2 ADAM10 25361965 interaction type N/A PTMCode2
ADAM10 EFNA2 25361965 interaction type N/A PTMCode2
EFNA2 EPHA4 25361965 interaction type N/A PTMCode2
EPHA4 EFNA2 25361965 interaction type N/A PTMCode2
EFNA2 EPHA3 25361965 interaction type N/A PTMCode2
EPHA3 EFNA2 25361965 interaction type N/A PTMCode2
EFNA2 EPHA2 25361965 interaction type N/A PTMCode2
EPHA2 EFNA2 25361965 interaction type N/A PTMCode2
EFNA2 EPHA7 25361965 interaction type N/A PTMCode2
EPHA7 EFNA2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EPHA2 EFNA2 14525934 25348397 8755474 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
EFNA2 EPHA3 14525934 25348397 9751130 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
EFNA2 EPHA5 10531456 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
EFNA2 ADAM10 10958785 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
EFNA2 ZHX1 25348397 N/A physical interaction ComPPI
EFNA2 EPHA7 25348397 N/A physical interaction ComPPI
EFNA2 BAP1 25348397 N/A physical interaction ComPPI
EFNA2 EPHA4 19836338 24234451 25348397 physical association molecular sieving,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,surface plasmon resonance array ComPPI,IntAct
EFNA2 EPHA2 10072375 27898060 8755474 stimulant N/A OmniPath
EFNA2 EPHA4 19836338 27898060 9330863 stimulant N/A OmniPath
EFNA2 EPHA7 27898060 9330863 stimulant N/A OmniPath
EPHA3 EFNA2 15114347 27898060 9751130 N/A N/A OmniPath
EFNA2 EPHA6 10072375 27898060 9330863 stimulant N/A OmniPath
EFNA2 EPHA5 10072375 10531456 27898060 stimulant N/A OmniPath
EFNA2 EPHA8 27898060 9330863 stimulant N/A OmniPath

Visualization










  Return