Gene Information gene info

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GENE：EFS

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EFS
FullNmae embryonal Fyn-associated substrate
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16898
EnsembleID ENSG00000100842
Uniprot O43281

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EFS immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EFS GO:0005515,GO:0005737,GO:0005886,GO:0005925,GO:0007155,GO:0007169,GO:0016477,GO:0017124,GO:0019904,GO:0035556

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PLCG1 EFS 17474147 23180781 physical association peptide array InnateDB
BLK EFS 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
EFS ABL1 20005715 interaction type N/A PSP,SignaLink
EFS SRC 20005715 interaction type N/A PSP,SignaLink
EFS PLCG1 20005715 interaction type N/A PSP,SignaLink
EFS PTK2 20005715 interaction type N/A PSP,SignaLink
EFS PTK2B 20005715 interaction type N/A PSP
EFS PTK2B 18988627 20005715 20005715 9750131 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
YBX1 EFS 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF EFS 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 EFS 20304954 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
SORBS3 EFS 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TRAPPC6A EFS 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CRK EFS 17474147 24234451 25348397 physical association peptide array,physical interaction ComPPI,IntAct
PTK2B EFS 14525934 25348397 9750131 N/A experimental interaction detection,in vitro ComPPI,HPRD
NUP155 EFS 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PIK3R1 EFS 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SRC EFS 17474147 24234451 25348397 27898060 8647432 physical association peptide array,physical interaction ComPPI,IntAct,OmniPath
NCK1 EFS 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
GRB2 EFS 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
BLK EFS 24234451 25348397 25416956 physical association physical interaction,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBC EFS 25348397 N/A physical interaction ComPPI
PTPN12 EFS 14525934 25348397 9748319 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SORBS2 EFS 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ABI2 EFS 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FYN EFS 12471123 24234451 25348397 25416956 27898060 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
LYST EFS 25348397 N/A physical interaction ComPPI
NLGN3 EFS 25348397 N/A physical interaction ComPPI
EFS SH2D3C 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
EFS BCAR1 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
EFS APP 25348397 N/A physical interaction ComPPI
EFS NPAS2 25348397 N/A physical interaction ComPPI
EFS ZNF417 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EFS ABL1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
EFS PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
OSTF1 EFS 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TSSK1B EFS 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BDKRB2 EFS 24234451 28298427 physical association ubiquitin reconstruction IntAct
EFS IWS1 24838002 27898060 N/A N/A OmniPath

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