Gene Information gene info

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GENE：EPHB3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EPHB3
FullNmae EPH receptor B3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3394
EnsembleID ENSG00000182580
Uniprot P54753

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EPHB3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EPHB3 GO:0001525,GO:0001655,GO:0005003,GO:0005005,GO:0005515,GO:0005524,GO:0005576,GO:0005829,GO:0005886,GO:0005886,GO:0006468,GO:0007411,GO:0007411,GO:0007413,GO:0008046,GO:0016477,GO:0021952,GO:0022038,GO:0022407,GO:0030425,GO:0031290,GO:0034446,GO:0043087,GO:0046777,GO:0048013,GO:0048013,GO:0048538,GO:0048546,GO:0050770,GO:0051965,GO:0060021,GO:0060996,GO:0060997

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EPHB3 hsa:2049 path:hsa04360 Axon guidance - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EFNB3 EPHB3 18988627 21071413 23331499 9267020 9484836 stimulation N/A SignaLink,SignaLink
EFNB1 EPHB3 23331499 9576626 stimulation N/A SignaLink
EFNB2 EPHB3 23331499 9576626 stimulation N/A SignaLink
EPHB3 RASA1 23331499 9674711 stimulation N/A SignaLink
EPHB3 AFDN 23331499 9707552 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
CRK EPHB3 20005715 interaction type N/A PSP,SignaLink
AFDN EPHB3 20005715 interaction type N/A PSP,SignaLink

Source Target Pmid Interactiontype Methods Database
ESR1 EPHB3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 EPHB3 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 EPHB3 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 EPHB3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 EPHB3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
E2F1 EPHB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EPHB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EPHB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000007F792 EPHB3 19536157 21572407 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000148B91 EPHB3 19536157 21572407 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000076B539 EPHB3 19536157 21572407 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000116F83 EPHB3 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000007A060 EPHB3 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000A939F EPHB3 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EPHB3 EPHB3 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
HPCAL1 EPHB3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRK EPHB3 14525934 25348397 9674711 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PKM EPHB3 25348397 N/A protein kinase assay ComPPI
EFNB2 EPHB3 25348397 N/A physical interaction ComPPI
RASA1 EPHB3 14525934 25348397 9674711 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
FYN EPHB3 14525934 25348397 9674711 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
EPHB3 EFNB3 14525934 25348397 9484836 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EPHB3 RYK 11956217 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
EPHB3 AFDN 24234451 25348397 9707552 physical association two hybrid,physical interaction ComPPI,IntAct
EPHB3 LNX1 25348397 N/A physical interaction ComPPI
EPHB3 GBE1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EPHB3 NFRKB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EPHB3 RUSF1 25348397 N/A physical interaction ComPPI
EPHB3 ADGRG5 25348397 N/A physical interaction ComPPI
EPHB3 HSF2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EPHB3 EPHB3 14525934 9674711 N/A experimental interaction detection HPRD
EPHB3 PTPN1 11579209 27898060 N/A N/A OmniPath
AFDN EPHB3 27898060 9707552 N/A N/A OmniPath
EFNB2 EPHB3 27898060 8559144 9330863 stimulant N/A OmniPath
EFNB1 EPHB3 27898060 9330863 stimulant N/A OmniPath
EFNB3 EPHB3 27898060 9330863 9484836 stimulant N/A OmniPath

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