GENE:FBXO32
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | FBXO32 |
| FullNmae | F-box protein 32 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16731 |
| EnsembleID | ENSG00000156804 |
| Uniprot | Q969P5 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| FBXO32 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| FBXO32 | GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0014894,GO:0016567,GO:0016567,GO:0016567,GO:0019005,GO:0019005,GO:0030018,GO:0071549 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| FBXO32 | hsa:114907 | path:hsa04068 | FoxO signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | FBXO32 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | FBXO32 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | FBXO32 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXO3 | FBXO32 | 18226221 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TP73 | FBXO32 | 21245298 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| TP63 | FBXO32 | 17521434 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | FBXO32 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | FBXO32 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | FBXO32 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | FBXO32 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | FBXO32 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | FBXO32 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | FBXO32 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | FBXO32 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | FBXO32 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EZH2 | FBXO32 | 21546904 24213577 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SMAD4 | FBXO32 | 20065949 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDKN1A | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| MYOG | FBXO32 | 23414517 24234451 25348397 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
| SKP1 | FBXO32 | 11717410 14525934 23414517 24234451 25348397 | physical association | experimental interaction detection,physical interaction,two hybrid fragment pooling approach | ComPPI,HPRD,IntAct |
| MYOD1 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| CTBP1 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| RBX1 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| DUSP1 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| EIF3F | FBXO32 | 18354498 19073596 24234451 25348397 27898060 | colocalization,physical association | anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,fluorescence microscopy | ComPPI,IntAct,OmniPath |
| AP1G1 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| CUL1 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| PSMC4 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| CDC34 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| MYBPC3 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| KLF4 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| SH3GL3 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| SSB | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| SH3GL2 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2D3 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| KHDRBS3 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| MLH1 | FBXO32 | 20706999 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| SH3GL1 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| SPTLC1 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| SLC25A10 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| MAVS | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| GMPS | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| MRPL12 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| FBXO25 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| KDM2A | FBXO32 | 23414517 24234451 25348397 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
| IGF2BP1 | FBXO32 | 25348397 | N/A | physical interaction | ComPPI |
| FBXO32 | SERPINB5 | 25348397 | N/A | physical interaction | ComPPI |
| YTHDC1 | FBXO32 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| FBXO32 | SLAMF6 | 23824909 30476227 | physical association | affinity chromatography technology | TheBiogrid |
| FBXO32 | H4C1 | 23824909 30476227 | physical association | affinity chromatography technology | TheBiogrid |
| FBXO32 | ZFYVE27 | 23824909 30476227 | physical association | affinity chromatography technology | TheBiogrid |
| FBXO32 | HSPB6 | 23824909 30476227 | physical association | affinity chromatography technology | TheBiogrid |
| FBXO32 | TIRAP | 23824909 30476227 | physical association | affinity chromatography technology | TheBiogrid |
| FBXO32 | ZNF428 | 23824909 30476227 | physical association | affinity chromatography technology | TheBiogrid |
| FBXO32 | MYOD1 | 15531760 19319192 21454680 22673621 27898060 | inhibition | N/A | OmniPath |
