Gene Information gene info

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GENE：GPC4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GPC4
FullNmae glypican 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4452
EnsembleID ENSG00000076716
Uniprot O75487

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GPC4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GPC4 GO:0005515,GO:0005634,GO:0005796,GO:0005886,GO:0009897,GO:0009966,GO:0009986,GO:0016055,GO:0016477,GO:0043202,GO:0045202,GO:0062023,GO:0070062,GO:0098696,GO:0098978,GO:0099560,GO:1905606

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GPC4 hsa:2239 path:hsa04310 Wnt signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR GPC4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 GPC4 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 GPC4 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 GPC4 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 GPC4 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF GPC4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 GPC4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GPC4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 GPC4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001F0C23 GPC4 22644326 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00001E0AEA GPC4 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 GPC4 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 GPC4 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 GPC4 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002E628F GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005E6F45 GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002AAD6B GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000033EBB8 GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E177F GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 GPC4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B GPC4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F GPC4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 GPC4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 GPC4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 GPC4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 GPC4 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA GPC4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004B83FE GPC4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000224AEA GPC4 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 GPC4 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 GPC4 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 GPC4 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 GPC4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 GPC4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 GPC4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D GPC4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E GPC4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 GPC4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D793 GPC4 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FGF2 GPC4 25361965 interaction type N/A PTMCode2
GPC4 FGF2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BAG3 GPC4 25348397 N/A physical interaction ComPPI
PICK1 GPC4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACP5 GPC4 12009023 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
GPC4 COL18A1 11336704 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GPC4 FGF2 11066092 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
GPC4 SQSTM1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GPC4 IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GPC4 GPR183 25348397 N/A physical interaction ComPPI
GPC4 ASCC2 25348397 N/A physical interaction ComPPI
GPC4 PTEN 25348397 N/A physical interaction ComPPI
GPC4 SPICE1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GPC4 AKAP9 25348397 N/A physical interaction ComPPI
GPC4 ABHD17A 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GPC4 CCNC 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GPC4 GPC6 25348397 N/A physical interaction ComPPI
GPC4 CAMKV 25348397 N/A physical interaction ComPPI
GPC4 SPCS2 25348397 N/A physical interaction ComPPI
GPC4 SCGB2A2 25348397 N/A physical interaction ComPPI
GPC4 MPPE1 25348397 N/A physical interaction ComPPI
GPC4 ADAM21 25348397 N/A physical interaction ComPPI
GPC4 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GPC4 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
GPC4 PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
GPC4 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
CSNK2A2 GPC4 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SOX2 GPC4 25348397 N/A physical interaction ComPPI
L1TD1 GPC4 24234451 25702638 association anti bait coimmunoprecipitation IntAct
GPC4 WNT5A 22302992 27898060 stimulant N/A OmniPath
GPC4 WNT3A 22302992 27898060 stimulant N/A OmniPath

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