Gene Information gene info

GENE:GTF2A1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GTF2A1
FullNmae general transcription factor IIA subunit 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4646
EnsembleID ENSG00000165417
Uniprot P52655

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GTF2A1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GTF2A1 GO:0000979,GO:0001091,GO:0003677,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005669,GO:0005672,GO:0005672,GO:0005672,GO:0005829,GO:0006366,GO:0006366,GO:0016251,GO:0016251,GO:0017025,GO:0045944,GO:0046982,GO:0051123,GO:0060261,GO:0061629,GO:0097550

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GTF2A1 hsa:2957 path:hsa03022 Basal transcription factors - Homo sapiens (human)
GTF2A1 hsa:2957 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 GTF2A1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 GTF2A1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 GTF2A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GTF2A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GTF2A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GTF2A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GTF2A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GTF2A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GTF2A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 GTF2A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GTF2A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GTF2A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 GTF2A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000016FF9C GTF2A1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000009262D GTF2A1 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F0F49 GTF2A1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000003ABC4 GTF2A1 20371350 22012620 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 GTF2A1 20371350 22012620 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000015F70F GTF2A1 20371350 22012620 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 GTF2A1 20371350 22012620 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C GTF2A1 20371350 22012620 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA GTF2A1 20371350 22012620 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 GTF2A1 22012620 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000B59A2 GTF2A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 GTF2A1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 GTF2A1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F GTF2A1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 GTF2A1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 GTF2A1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000042619A GTF2A1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000017DBB8 GTF2A1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000412AC7 GTF2A1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000759EB8 GTF2A1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 GTF2A1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 GTF2A1 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5E03 GTF2A1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 GTF2A1 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000054DF42 GTF2A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001DA458 GTF2A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001B12A4 GTF2A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 GTF2A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006A1CB GTF2A1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075C3F6 GTF2A1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000171020 GTF2A1 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TAF1 GTF2A1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PSMC6 GTF2A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GTF2A1 GTF2A2 14525934 24234451 25348397 25416956 7724559 7958900 8626665 physical association two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
GTF2A1 GTF2E1 11509574 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GTF2A1 GTF2E2 11509574 14525934 25348397 9618479 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GTF2A1 GTF2F1 11509574 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GTF2A1 TAF1 11278496 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
GTF2A1 BCL3 14525934 25348397 9812988 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GTF2A1 TBP 14525934 24234451 25348397 8006019 physical association experimental interaction detection,physical interaction,biochemical,in vitro ComPPI,HPRD,IntAct
GTF2A1 TRIP4 10454579 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GTF2A1 TAF4 11564872 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GTF2A1 CSNK2A1 11278496 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
GTF2A1 CSNK2A2 11278496 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
GTF2A1 TASP1 14525934 16537915 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
GTF2A1 NCOA6 25348397 N/A physical interaction ComPPI
GTF2A1 HMGB1 25348397 N/A physical interaction ComPPI
GTF2A1 GCN1 25348397 N/A physical interaction ComPPI
GTF2A1 HSPA9 25348397 N/A physical interaction ComPPI
GTF2A1 TAF6 25348397 N/A physical interaction ComPPI
GTF2A1 TAF5 25348397 N/A physical interaction ComPPI
GTF2A1 DOCK7 25348397 N/A physical interaction ComPPI
GTF2A1 CNOT1 25348397 N/A physical interaction ComPPI
GTF2A1 TBPL2 25348397 N/A physical interaction ComPPI
GTF2A1 HNRNPA1 25348397 N/A physical interaction ComPPI
GTF2A1 MYLK2 25348397 N/A physical interaction ComPPI
GTF2A1 KDM5B 25348397 N/A physical interaction ComPPI
GTF2A1 MKX 25348397 N/A physical interaction ComPPI
GTF2A1 CREB1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
GTF2A1 TERF2 25348397 N/A physical interaction ComPPI
GTF2A1 SIRT1 25348397 N/A physical interaction ComPPI
GTF2A1 ZEB1 25348397 N/A physical interaction ComPPI
GTF2A1 TAF4B 25348397 N/A physical interaction ComPPI
GTF2A1 BOP1 25348397 N/A physical interaction ComPPI
GTF2A1 GARS1 25348397 N/A physical interaction ComPPI
GTF2A1 GORASP2 25348397 N/A physical interaction ComPPI
GTF2A1 ATG7 25348397 N/A physical interaction ComPPI
GTF2A1 BLMH 25348397 N/A physical interaction ComPPI
GTF2A1 NIBAN2 25348397 N/A physical interaction ComPPI
GTF2A1 SARS1 25348397 N/A physical interaction ComPPI
GTF2A1 SNX6 25348397 N/A physical interaction ComPPI
GTF2A1 ME1 25348397 N/A physical interaction ComPPI
GTF2A1 PDIA6 25348397 N/A physical interaction ComPPI
GTF2A1 RDX 25348397 N/A physical interaction ComPPI
GTF2A1 RPUSD2 25348397 N/A physical interaction ComPPI
GTF2A1 TBCD 25348397 N/A physical interaction ComPPI
GTF2A1 UGDH 25348397 N/A physical interaction ComPPI
GTF2A1 HUWE1 25348397 N/A physical interaction ComPPI
GTF2A1 NFYA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GTF2A1 SHMT2 25348397 N/A physical interaction ComPPI
GTF2A1 CUEDC2 25348397 N/A physical interaction ComPPI
GTF2A1 CYBC1 25348397 N/A physical interaction ComPPI
GTF2A1 INPPL1 25348397 N/A physical interaction ComPPI
GTF2A1 PTCD2 25348397 N/A physical interaction ComPPI
GTF2A1 PTMA 25348397 N/A physical interaction ComPPI
GTF2A1 EWSR1 25348397 N/A physical interaction ComPPI
GTF2A1 BCAT1 25348397 N/A physical interaction ComPPI
GTF2A1 SCHIP1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
GTF2A1 BIRC7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GTF2A1 FAM20C 22582013 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
GTF2A1 POLR2E 24234451 25348397 27193682 physical association electron tomography ComPPI,IntAct
GTF2A1 ERCC2 24234451 25348397 27193682 physical association electron tomography ComPPI,IntAct
LMNA GTF2A1 25348397 N/A physical interaction ComPPI
PRR20D GTF2A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SP4 GTF2A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBPL1 GTF2A1 10570139 14525934 17353931 17643375 24234451 24835508 25348397 26186194 27898060 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct,OmniPath
ATP6V1C1 GTF2A1 25348397 N/A physical interaction ComPPI
SRC GTF2A1 11278496 27898060 N/A N/A OmniPath
TAF1 GTF2A1 11278496 17081983 18452278 27898060 stimulant N/A OmniPath
CSNK2A1 GTF2A1 11278496 18452278 27898060 N/A N/A OmniPath
CSNK2A2 GTF2A1 11278496 18452278 27898060 N/A N/A OmniPath
TASP1 GTF2A1 16537915 27898060 stimulant N/A OmniPath

Visualization