GENE:GTF2A1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | GTF2A1 |
FullNmae | general transcription factor IIA subunit 1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:4646 |
EnsembleID | ENSG00000165417 |
Uniprot | P52655 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
GTF2A1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
GTF2A1 | GO:0000979,GO:0001091,GO:0003677,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005669,GO:0005672,GO:0005672,GO:0005672,GO:0005829,GO:0006366,GO:0006366,GO:0016251,GO:0016251,GO:0017025,GO:0045944,GO:0046982,GO:0051123,GO:0060261,GO:0061629,GO:0097550 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
GTF2A1 | hsa:2957 | path:hsa03022 | Basal transcription factors - Homo sapiens (human) |
GTF2A1 | hsa:2957 | path:hsa05203 | Viral carcinogenesis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | GTF2A1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXP3 | GTF2A1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | GTF2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | GTF2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | GTF2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | GTF2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | GTF2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | GTF2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | GTF2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
GATA2 | GTF2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | GTF2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | GTF2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | GTF2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS000016FF9C | GTF2A1 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS000009262D | GTF2A1 | 18591254 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000F0F49 | GTF2A1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000003ABC4 | GTF2A1 | 20371350 22012620 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004AF715 | GTF2A1 | 20371350 22012620 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000015F70F | GTF2A1 | 20371350 22012620 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000254A6 | GTF2A1 | 20371350 22012620 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075994C | GTF2A1 | 20371350 22012620 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005606AA | GTF2A1 | 20371350 22012620 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000D2680 | GTF2A1 | 22012620 23592263 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000B59A2 | GTF2A1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000215483 | GTF2A1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001A7F58 | GTF2A1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000B989F | GTF2A1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002FC5B0 | GTF2A1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C85B2 | GTF2A1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000042619A | GTF2A1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000017DBB8 | GTF2A1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000412AC7 | GTF2A1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000759EB8 | GTF2A1 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000039E1E1 | GTF2A1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002233F4 | GTF2A1 | 20371350 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003E5E03 | GTF2A1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000427B68 | GTF2A1 | 20371350 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000054DF42 | GTF2A1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001DA458 | GTF2A1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001B12A4 | GTF2A1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000331800 | GTF2A1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000006A1CB | GTF2A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075C3F6 | GTF2A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000171020 | GTF2A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
TAF1 | GTF2A1 | 22135298 | phosphorylation | N/A | PhosphoSite |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PSMC6 | GTF2A1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
GTF2A1 | GTF2A2 | 14525934 24234451 25348397 25416956 7724559 7958900 8626665 | physical association | two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid | ComPPI,HPRD,IntAct |
GTF2A1 | GTF2E1 | 11509574 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
GTF2A1 | GTF2E2 | 11509574 14525934 25348397 9618479 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
GTF2A1 | GTF2F1 | 11509574 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
GTF2A1 | TAF1 | 11278496 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
GTF2A1 | BCL3 | 14525934 25348397 9812988 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
GTF2A1 | TBP | 14525934 24234451 25348397 8006019 | physical association | experimental interaction detection,physical interaction,biochemical,in vitro | ComPPI,HPRD,IntAct |
GTF2A1 | TRIP4 | 10454579 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
GTF2A1 | TAF4 | 11564872 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
GTF2A1 | CSNK2A1 | 11278496 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
GTF2A1 | CSNK2A2 | 11278496 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
GTF2A1 | TASP1 | 14525934 16537915 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
GTF2A1 | NCOA6 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | HMGB1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | GCN1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | HSPA9 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | TAF6 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | TAF5 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | DOCK7 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | CNOT1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | TBPL2 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | HNRNPA1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | MYLK2 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | KDM5B | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | MKX | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | CREB1 | 20936779 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
GTF2A1 | TERF2 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | SIRT1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | ZEB1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | TAF4B | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | BOP1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | GARS1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | GORASP2 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | ATG7 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | BLMH | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | NIBAN2 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | SARS1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | SNX6 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | ME1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | PDIA6 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | RDX | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | RPUSD2 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | TBCD | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | UGDH | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | HUWE1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | NFYA | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
GTF2A1 | SHMT2 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | CUEDC2 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | CYBC1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | INPPL1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | PTCD2 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | PTMA | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | EWSR1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | BCAT1 | 25348397 | N/A | physical interaction | ComPPI |
GTF2A1 | SCHIP1 | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
GTF2A1 | BIRC7 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
GTF2A1 | FAM20C | 22582013 24234451 25348397 | phosphorylation reaction | protein kinase assay | ComPPI,IntAct |
GTF2A1 | POLR2E | 24234451 25348397 27193682 | physical association | electron tomography | ComPPI,IntAct |
GTF2A1 | ERCC2 | 24234451 25348397 27193682 | physical association | electron tomography | ComPPI,IntAct |
LMNA | GTF2A1 | 25348397 | N/A | physical interaction | ComPPI |
PRR20D | GTF2A1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
SP4 | GTF2A1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
TBPL1 | GTF2A1 | 10570139 14525934 17353931 17643375 24234451 24835508 25348397 26186194 27898060 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach | ComPPI,HPRD,IntAct,OmniPath |
ATP6V1C1 | GTF2A1 | 25348397 | N/A | physical interaction | ComPPI |
SRC | GTF2A1 | 11278496 27898060 | N/A | N/A | OmniPath |
TAF1 | GTF2A1 | 11278496 17081983 18452278 27898060 | stimulant | N/A | OmniPath |
CSNK2A1 | GTF2A1 | 11278496 18452278 27898060 | N/A | N/A | OmniPath |
CSNK2A2 | GTF2A1 | 11278496 18452278 27898060 | N/A | N/A | OmniPath |
TASP1 | GTF2A1 | 16537915 27898060 | stimulant | N/A | OmniPath |