Gene Information gene info

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GENE：IL17RA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IL17RA
FullNmae interleukin 17 receptor A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5985
EnsembleID ENSG00000177663
Uniprot Q96F46

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IL17RA immunogenic 37275552 To identify genes associated with ICD, we collected 34 ICD-related genes from previously reported literature retulator signature

Go Annotation:

GeneSymbol Go id
IL17RA GO:0005102,GO:0005515,GO:0005576,GO:0005886,GO:0005886,GO:0005886,GO:0006954,GO:0007166,GO:0009615,GO:0030163,GO:0030368,GO:0030368,GO:0030368,GO:0032736,GO:0032747,GO:0032754,GO:0032755,GO:0038173,GO:0045087,GO:0050729,GO:0050832,GO:0071621,GO:0072537,GO:0072538,GO:0097400,GO:0097400,GO:1900017,GO:2000340

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IL17RA hsa:23765 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
IL17RA hsa:23765 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)
IL17RA hsa:23765 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL17RA TRAF6 17277779 17346928 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL17RA IL17RD 19079364 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL17RA IL17A 11058597 17911633 18684971 19838198 23180781 9367539 physical association fluorescence-activated cell sorting,surface plasmon resonance,competition binding,solid phase assay InnateDB
IL17RA IL17RC 16785495 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL17RA IL17F 18684971 19838198 23180781 physical association surface plasmon resonance,solid phase assay InnateDB
IL17A IL17RA 19838198 23180781 physical association surface plasmon resonance InnateDB
IL17F IL17RA 19838198 23180781 physical association surface plasmon resonance InnateDB
IL25 IL17RA 19838198 23180781 physical association surface plasmon resonance InnateDB
IL17RA TRAF3IP2 17035243 17277779 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL17RA TRAF3 17277779 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL17RA MAP3K7 17277779 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF3IP2 IL17RA 17277779 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL17RE IL17RA 21993848 21993849 23834281 29145629 physical association inferred by curator Reactome
IL17RC IL17RA 11574464 16397230 16785495 29145629 8777726 physical association inferred by curator Reactome
IL17RA IL17RB 24243840 29145629 physical association inferred by curator Reactome
IL17RA IL25 24243840 29145629 physical association inferred by curator Reactome

Source Target Pmid Interactiontype Methods Database
ETS1 IL17RA 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 IL17RA 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 IL17RA 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 IL17RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IL17RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 IL17RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 IL17RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 IL17RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 IL17RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR IL17RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 IL17RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 IL17RA 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS000001C659 IL17RA 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000024CEE0 IL17RA 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 IL17RA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F373E IL17RA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 IL17RA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004AC389 IL17RA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA IL17RA 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GSK3B IL17RA 22135298 phosphorylation N/A PhosphoSite
GSK3A IL17RA 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
TRAF6 IL17RA 17277779 17346928 25348397 27898060 N/A physical interaction ComPPI,OmniPath
IQGAP3 IL17RA 25348397 N/A physical interaction ComPPI
SIK2 IL17RA 25348397 N/A physical interaction ComPPI
SYK IL17RA 25348397 N/A physical interaction ComPPI
TTF2 IL17RA 25348397 N/A physical interaction ComPPI
SLAMF1 IL17RA 25348397 N/A physical interaction ComPPI
HDAC3 IL17RA 25348397 N/A physical interaction ComPPI
NCOR1 IL17RA 25348397 N/A physical interaction ComPPI
RPS6KA2 IL17RA 25348397 N/A physical interaction ComPPI
TRAF3 IL17RA 25348397 N/A physical interaction ComPPI
TUBA4A IL17RA 25348397 N/A physical interaction ComPPI
RPS6KA3 IL17RA 25348397 N/A physical interaction ComPPI
RPS6KA1 IL17RA 25348397 N/A physical interaction ComPPI
TBCD IL17RA 25348397 N/A physical interaction ComPPI
HTT IL17RA 25348397 N/A physical interaction ComPPI
MAP3K7 IL17RA 25348397 N/A physical interaction ComPPI
TBL1X IL17RA 25348397 N/A physical interaction ComPPI
NR3C1 IL17RA 25348397 N/A physical interaction ComPPI
BCOR IL17RA 25348397 N/A physical interaction ComPPI
ZBTB33 IL17RA 25348397 N/A physical interaction ComPPI
TRAF3IP2 IL17RA 17035243 17277779 22045852 24120361 25202827 25348397 27898060 N/A physical interaction ComPPI,OmniPath
LRIF1 IL17RA 25348397 N/A physical interaction ComPPI
OS9 IL17RA 25348397 N/A physical interaction ComPPI
TBL1XR1 IL17RA 25348397 N/A physical interaction ComPPI
BRIP1 IL17RA 25348397 N/A physical interaction ComPPI
PKN3 IL17RA 25348397 N/A physical interaction ComPPI
TRPS1 IL17RA 25348397 N/A physical interaction ComPPI
IL17A IL17RA 14525934 25348397 9367539 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
IL17RA SUSD4 25348397 N/A physical interaction ComPPI
IL17RA DNASE2B 25348397 N/A physical interaction ComPPI
IL17RA KIAA0586 25348397 N/A physical interaction ComPPI
IL17RA TUBB1 25348397 N/A physical interaction ComPPI
IL17RA DDX12P 25348397 N/A physical interaction ComPPI
IL17RA DDX11 25348397 N/A physical interaction ComPPI
IL17RA PLCH1 25348397 N/A physical interaction ComPPI
IL17RA PLEKHA5 25348397 N/A physical interaction ComPPI
IL17RA ZNF318 25348397 N/A physical interaction ComPPI
IL17RA RICTOR 25348397 N/A physical interaction ComPPI
IL17RA KIAA1671 25348397 N/A physical interaction ComPPI
IL17RA C5ORF34 25348397 N/A physical interaction ComPPI
IL17RA ACAD11 25348397 N/A physical interaction ComPPI
IL17RA GTSE1 25348397 N/A physical interaction ComPPI
IL17RA PPIP5K2 25348397 N/A physical interaction ComPPI
IL17RA SMG8 25348397 N/A physical interaction ComPPI
IL17RA MCM8 25348397 N/A physical interaction ComPPI
IL17RA MAP7 25348397 N/A physical interaction ComPPI
IL17RA HASPIN 25348397 N/A physical interaction ComPPI
IL17RA USP54 25348397 N/A physical interaction ComPPI
IL17RA ICE2 25348397 N/A physical interaction ComPPI
IL17RA ANKHD1 25348397 N/A physical interaction ComPPI
IL17RA HAUS5 25348397 N/A physical interaction ComPPI
IL17RA MAP7D2 25348397 N/A physical interaction ComPPI
IL17RA BCAS3 25348397 N/A physical interaction ComPPI
IL17RA EIF4E2 25348397 N/A physical interaction ComPPI
IL17RA LYZL1 25348397 N/A physical interaction ComPPI
IL17RA ZPBP2 25348397 N/A physical interaction ComPPI
IL17RA CCDC88A 25348397 N/A physical interaction ComPPI
IL17RA ZNF644 25348397 N/A physical interaction ComPPI
IL17RA IDS 25348397 N/A physical interaction ComPPI
IL17RA MKS1 25348397 N/A physical interaction ComPPI
IL17RA ZNHIT6 25348397 N/A physical interaction ComPPI
IL17RA TEDC1 25348397 N/A physical interaction ComPPI
IL17RA CBWD1 25348397 N/A physical interaction ComPPI
IL17RA TASOR 25348397 N/A physical interaction ComPPI
IL17RA PRG3 25348397 N/A physical interaction ComPPI
IL17RA SIMC1 25348397 N/A physical interaction ComPPI
IL17RA C15ORF39 25348397 N/A physical interaction ComPPI
IL17RA DYNC2H1 25348397 N/A physical interaction ComPPI
IL17RA YEATS2 25348397 N/A physical interaction ComPPI
IL17RA ESPL1 25348397 N/A physical interaction ComPPI
IL17RA IL17RE 21993848 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
IL17RC IL17RA 16785495 27898060 N/A N/A OmniPath
IL17A IL17RA 11058597 17911633 18684971 19838198 27898060 9367539 stimulant N/A OmniPath
IL17F IL17RA 18684971 19838198 27898060 N/A N/A OmniPath

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