Gene Information gene info

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GENE：IL1RL1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IL1RL1
FullNmae interleukin 1 receptor like 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5998
EnsembleID ENSG00000115602
Uniprot Q01638

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IL1RL1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IL1RL1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IL1RL1 GO:0002113,GO:0002114,GO:0002826,GO:0004896,GO:0004908,GO:0005515,GO:0005576,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005925,GO:0006954,GO:0006955,GO:0007165,GO:0009897,GO:0030225,GO:0032689,GO:0032722,GO:0032754,GO:0038172,GO:0043032,GO:0050135,GO:0050729,GO:0061809

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IL1RL1 hsa:9173 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRAK4 IL1RL1 12538665 15084582 16286016 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL33 IL1RL1 18450470 19439663 19559631 23180781 physical association anti tag coimmunoprecipitation,dynamic light scattering,pull down InnateDB
IL1RL1 IL33 19836339 23180781 23980170 physical association molecular sieving,nuclear magnetic resonance,surface plasmon resonance,x-ray crystallography InnateDB
IL1RAP IL1RL1 19836339 23180781 physical association isothermal titration calorimetry,nuclear magnetic resonance InnateDB
TBX21 IL1RL1 23180781 23232398 physical association anti tag coimmunoprecipitation InnateDB
GATA3 IL1RL1 23180781 23232398 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 IL1RL1 19941826 22865859 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 IL1RL1 18971253 19941826 22865859 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 IL1RL1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 IL1RL1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 IL1RL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IL1RL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 IL1RL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 IL1RL1 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
IL1RL1 TRAF6 25361965 interaction type N/A PTMCode2
TRAF6 IL1RL1 25361965 interaction type N/A PTMCode2
IL1RL1 IRAK4 25361965 interaction type N/A PTMCode2
IRAK4 IL1RL1 25361965 interaction type N/A PTMCode2
IL1RL1 IL33 25361965 interaction type N/A PTMCode2
IL33 IL1RL1 25361965 interaction type N/A PTMCode2
IL1RL1 TIRAP 25361965 interaction type N/A PTMCode2
TIRAP IL1RL1 25361965 interaction type N/A PTMCode2
IL1RL1 MYD88 25361965 interaction type N/A PTMCode2
MYD88 IL1RL1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TRAF6 IL1RL1 16286016 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TIRAP IL1RL1 25348397 N/A in vitro ComPPI
IRAK1 IL1RL1 25348397 N/A physical interaction ComPPI
MYD88 IL1RL1 14525934 15004556 16286016 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
IRAK4 IL1RL1 16286016 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TMED1 IL1RL1 14525934 25348397 27898060 8621446 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
IL1RL1 IL33 14525934 16286016 24234451 25348397 N/A experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
IL1RL1 APP 25348397 N/A physical interaction ComPPI
IL1RL1 CLEC7A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
IL33 IL1RL1 16286016 18450470 19439663 19559631 19836339 23980170 27898060 N/A N/A OmniPath
IL1RL1 IRAK4 12538665 15084582 16286016 27898060 N/A N/A OmniPath
IRAK4 IL1RL1 12538665 15084582 16286016 27898060 N/A N/A OmniPath

Visualization










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