Gene Information gene info

GENE:KRT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KRT1
FullNmae keratin 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6412
EnsembleID ENSG00000167768
Uniprot P04264

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KRT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KRT1 GO:0001533,GO:0001867,GO:0001895,GO:0005515,GO:0005576,GO:0005615,GO:0005634,GO:0005737,GO:0005829,GO:0005856,GO:0006979,GO:0016020,GO:0016020,GO:0018149,GO:0030246,GO:0030280,GO:0030280,GO:0031424,GO:0038023,GO:0042730,GO:0045095,GO:0045095,GO:0045109,GO:0045765,GO:0046982,GO:0050728,GO:0051290,GO:0061436,GO:0062023,GO:0070062,GO:0072562,GO:1904813

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PITX3 KRT1 22278372 23180781 physical association anti tag coimmunoprecipitation InnateDB
EED KRT1 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 KRT1 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 KRT1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 KRT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 KRT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RARB KRT1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
KRT1 ALB 25361965 interaction type N/A PTMCode2
ALB KRT1 25361965 interaction type N/A PTMCode2
KRT1 IVL 25361965 interaction type N/A PTMCode2
IVL KRT1 25361965 interaction type N/A PTMCode2
KRT5 KRT1 25361965 interaction type N/A PTMCode2
KRT1 KRT5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GOLGA2 KRT1 24234451 25348397 25910212 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
PIK3R2 KRT1 25348397 N/A physical interaction ComPPI
CUL5 KRT1 25348397 N/A physical interaction ComPPI
KRT19 KRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBASH3B KRT1 25348397 N/A physical interaction ComPPI
KRT38 KRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT5 KRT1 11591653 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
KRT2 KRT1 25348397 N/A physical interaction ComPPI
SGTB KRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGHG1 KRT1 15174051 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
NUP62 KRT1 24234451 25348397 25910212 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,split luciferase complementation,validated two hybrid ComPPI,IntAct
TRAF6 KRT1 25348397 N/A physical interaction ComPPI
GABARAPL2 KRT1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
U2AF1L5 KRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DCUN1D1 KRT1 25348397 N/A physical interaction ComPPI
KEAP1 KRT1 25348397 N/A physical interaction ComPPI
KRT33B KRT1 24234451 25348397 25910212 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,split luciferase complementation,validated two hybrid ComPPI,IntAct
MAP1LC3B KRT1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KRT31 KRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT77 KRT1 25348397 N/A physical interaction ComPPI
RINT1 KRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRK KRT1 25348397 N/A physical interaction ComPPI
CBL KRT1 25348397 N/A physical interaction ComPPI
SHC1 KRT1 25348397 N/A physical interaction ComPPI
PPP1R15A KRT1 24234451 25348397 29109149 association anti tag coimmunoprecipitation ComPPI,IntAct
GRB2 KRT1 25348397 N/A physical interaction ComPPI
COPS5 KRT1 25348397 N/A physical interaction ComPPI
USP7 KRT1 25348397 N/A physical interaction ComPPI
PRKCE KRT1 11897493 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
INPPL1 KRT1 25348397 N/A physical interaction ComPPI
CUL3 KRT1 25348397 N/A physical interaction ComPPI
APOA1 KRT1 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
APC KRT1 16212417 24234451 25348397 physical association surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
CDH1 KRT1 16212417 24234451 25348397 physical association surface plasmon resonance,physical interaction,surface plasmon resonance array ComPPI,IntAct
KNG1 KRT1 10066772 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HMG20A KRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
YWHAQ KRT1 14525934 15324660 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
PRSS1 KRT1 25348397 N/A physical interaction ComPPI
EPS15 KRT1 25348397 N/A physical interaction ComPPI
NEDD8 KRT1 25348397 N/A physical interaction ComPPI
CUL2 KRT1 25348397 N/A physical interaction ComPPI
CUL4B KRT1 25348397 N/A physical interaction ComPPI
EVPL KRT1 14525934 25348397 8999895 N/A experimental interaction detection,in vivo ComPPI,HPRD
FANCC KRT1 25348397 N/A physical interaction ComPPI
CSTA KRT1 25348397 N/A physical interaction ComPPI
CUL1 KRT1 25348397 N/A physical interaction ComPPI
ADRB2 KRT1 25348397 N/A physical interaction ComPPI
CUL4A KRT1 25348397 N/A physical interaction ComPPI
EGFR KRT1 15657067 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SFN KRT1 25348397 N/A physical interaction ComPPI
GABARAP KRT1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP1LC3A KRT1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
COPS6 KRT1 25348397 N/A physical interaction ComPPI
VCAM1 KRT1 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 KRT1 25348397 N/A physical interaction ComPPI
EED KRT1 25348397 N/A physical interaction ComPPI
F12 KRT1 11204562 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MBL2 KRT1 11549596 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
CAND1 KRT1 25348397 N/A physical interaction ComPPI
TFIP11 KRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AP2M1 KRT1 25348397 N/A physical interaction ComPPI
IGHM KRT1 15174051 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
FFAR2 KRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ESR1 KRT1 25348397 N/A physical interaction ComPPI
RPS6KB2 KRT1 25348397 N/A physical interaction ComPPI
TRIM27 KRT1 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,split luciferase complementation,validated two hybrid ComPPI,IntAct
CCNA2 KRT1 25348397 N/A physical interaction ComPPI
PI3 KRT1 25348397 N/A physical interaction ComPPI
TANK KRT1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
KRT1 CALB2 10942575 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
KRT1 DSP 14525934 25348397 9261168 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
KRT1 FANCA 25348397 N/A physical interaction ComPPI
KRT1 IVL 25348397 N/A physical interaction ComPPI
KRT1 LORICRIN 25348397 N/A physical interaction ComPPI
KRT1 POU5F1 25348397 N/A physical interaction ComPPI
KRT1 UCHL5 25348397 N/A physical interaction ComPPI
KRT1 TJP1 25348397 N/A physical interaction ComPPI
KRT1 HDGF 25348397 N/A physical interaction ComPPI
KRT1 KRT9 25348397 N/A physical interaction ComPPI
KRT1 KRT10 25348397 N/A physical interaction ComPPI
KRT1 SLC25A5 25348397 N/A physical interaction ComPPI
KRT1 MAGOH 25348397 N/A physical interaction ComPPI
KRT1 ALB 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
KRT1 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
KRT1 IQCB1 25348397 N/A physical interaction ComPPI
KRT1 PAN2 25348397 N/A physical interaction ComPPI
KRT1 LGR4 25348397 N/A physical interaction ComPPI
KRT1 HNRNPA1 25348397 N/A physical interaction ComPPI
KRT1 GAN 25348397 N/A physical interaction ComPPI
KRT1 UBE3A 25348397 N/A physical interaction ComPPI
KRT1 CPS1 25348397 N/A physical interaction ComPPI
KRT1 CYLD 25348397 N/A physical interaction ComPPI
KRT1 MAPK11 14676314 24234451 25348397 association coimmunoprecipitation ComPPI,IntAct
KRT1 IGHA1 15174051 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
KRT1 PPP2R2B 19156129 24234451 25348397 association anti tag coimmunoprecipitation,pull down ComPPI,IntAct
KRT1 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KRT1 E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
KRT1 KRT15 24234451 25348397 25910212 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,split luciferase complementation,validated two hybrid ComPPI,IntAct
KRT1 HAUS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 KRT34 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 KRT13 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 TRIM54 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 TLCD4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 KRT26 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 KRT24 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 KRT14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 KRT16 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 KRT37 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 KRT35 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 KRT25 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 KRT28 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 KRT39 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 KRT27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT1 GOLGA6L9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF4A3 KRT1 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
METTL3 KRT1 24234451 29507755 association anti tag coimmunoprecipitation IntAct
WTAP KRT1 24234451 29507755 association anti tag coimmunoprecipitation IntAct
METTL14 KRT1 24234451 29507755 association anti tag coimmunoprecipitation IntAct
KRT1 APC 18359618 27898060 stimulant N/A OmniPath
KRT1 MPO 17591979 27898060 stimulant N/A OmniPath
PLAUR KRT1 14691569 27898060 stimulant N/A OmniPath
C1QBP KRT1 14691569 27898060 stimulant N/A OmniPath

Visualization