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GENE：MAML3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MAML3
FullNmae mastermind like transcriptional coactivator 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16272
EnsembleID ENSG00000196782
Uniprot Q96JK9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MAML3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MAML3 GO:0003713,GO:0003713,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0007219,GO:0007221,GO:0016607,GO:0045944

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MAML3 hsa:55534 path:hsa04330 Notch signaling pathway - Homo sapiens (human)
MAML3 hsa:55534 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
MAML3 hsa:55534 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MAML3 NOTCH2 12370315 23331499 stimulation N/A SignaLink
MAML3 NOTCH3 12370315 23331499 stimulation N/A SignaLink
MAML3 NOTCH1 12370315 23331499 stimulation N/A SignaLink
MAML3 NOTCH4 12370315 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR MAML3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 MAML3 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MAML3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 MAML3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 MAML3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MAML3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000072E4C MAML3 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000E1E9E MAML3 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000211070 MAML3 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075BEA7 MAML3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 MAML3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 MAML3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000101787 MAML3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 MAML3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D MAML3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A MAML3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E92A8 MAML3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 MAML3 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000017EA6A MAML3 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00001B0D1E MAML3 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000042B108 MAML3 25416803 28735896 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NOTCH4 MAML3 12370315 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MAML1 MAML3 25348397 N/A physical interaction ComPPI
NOTCH1 MAML3 12370315 14525934 23022380 24234451 25348397 association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
HNRNPL MAML3 25348397 N/A physical interaction ComPPI
CDC20 MAML3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MAML3 NOTCH2 12370315 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MAML3 NOTCH3 12370315 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MAML3 NFX1 25348397 N/A physical interaction ComPPI
MAML3 SUPT5H 25348397 N/A physical interaction ComPPI
MAML3 RAI1 25348397 N/A physical interaction ComPPI
MAML3 ZBTB1 25348397 N/A physical interaction ComPPI
MAML3 SCMH1 25348397 N/A physical interaction ComPPI
MAML3 ZZZ3 25348397 N/A physical interaction ComPPI
MAML3 RBPJ 25348397 N/A physical interaction ComPPI
H2BC9 MAML3 24234451 30021884 physical association cross-linking study IntAct
RBPJ MAML3 21873209 27898060 stimulant N/A OmniPath
MAML3 NOTCH1 12370315 23022380 27898060 stimulant N/A OmniPath
MAML3 NOTCH2 12370315 27898060 stimulant N/A OmniPath
MAML3 NOTCH3 12370315 27898060 stimulant N/A OmniPath
MAML3 NOTCH4 12370315 27898060 stimulant N/A OmniPath
NOTCH4 MAML3 12370315 27898060 stimulant N/A OmniPath

Visualization










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