Gene Information gene info

GENE:MSI2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MSI2
FullNmae musashi RNA binding protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18585
EnsembleID ENSG00000153944
Uniprot Q96DH6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MSI2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MSI2 GO:0003723,GO:0003729,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0005844,GO:0006417,GO:0007417,GO:0008266,GO:0042802,GO:0043231,GO:0048864

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MSI2 hsa:124540 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SUZ12 MSI2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 MSI2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
BMI1 MSI2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR MSI2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MSI2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 MSI2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 MSI2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MSI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 MSI2 N/A 20584899 rna interference,inhibition experimental interaction detection,western blot miRSponge
URS0000338542 MSI2 18668040 20584899 25416803 mrna cleavage,inhibition experimental interaction detection,western blot TarBase
URS0000013DD8 MSI2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE MSI2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000292B1 MSI2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB MSI2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 MSI2 21572407 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 MSI2 22012620 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00003804D8 MSI2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004407DC MSI2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000FC8EB MSI2 22012620 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000019D79B MSI2 22012620 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000364FEF MSI2 22012620 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001799A3 MSI2 22012620 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004719AB MSI2 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS00003D8730 MSI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 MSI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 MSI2 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS000007D64A MSI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 MSI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 MSI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000A07C1 MSI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 MSI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D MSI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000237CBD MSI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000032EF64 MSI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 MSI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000237E04 MSI2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001B968D MSI2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075C4B1 MSI2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 MSI2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001012BC MSI2 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PIN1 MSI2 25348397 N/A physical interaction ComPPI
EIF3G MSI2 25348397 N/A physical interaction ComPPI
MEOX2 MSI2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FKBP1A MSI2 25348397 N/A physical interaction ComPPI
BMI1 MSI2 25348397 N/A physical interaction ComPPI
ANKRD40 MSI2 25348397 N/A physical interaction ComPPI
HNRNPH2 MSI2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GRB2 MSI2 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
UBE2L3 MSI2 25348397 N/A physical interaction ComPPI
CTSB MSI2 25348397 N/A physical interaction ComPPI
CUL3 MSI2 25348397 N/A physical interaction ComPPI
RAB7A MSI2 25348397 N/A physical interaction ComPPI
NTRK1 MSI2 25348397 N/A physical interaction ComPPI
STIP1 MSI2 25348397 N/A physical interaction ComPPI
RPA1 MSI2 25348397 N/A physical interaction ComPPI
PABPC4 MSI2 25348397 N/A physical interaction ComPPI
HNRNPL MSI2 25348397 N/A physical interaction ComPPI
PABPC1 MSI2 25348397 N/A physical interaction ComPPI
CILK1 MSI2 25348397 N/A physical interaction ComPPI
RPA2 MSI2 25348397 N/A physical interaction ComPPI
RPA3 MSI2 25348397 N/A physical interaction ComPPI
MDM2 MSI2 25348397 N/A physical interaction ComPPI
SOX2 MSI2 25348397 N/A physical interaction ComPPI
RNF2 MSI2 25348397 N/A physical interaction ComPPI
SF1 MSI2 24234451 25348397 26420826 physical association two hybrid fragment pooling approach ComPPI,IntAct
VCAM1 MSI2 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
HNRNPH1 MSI2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WDR1 MSI2 25348397 N/A physical interaction ComPPI
H2AX MSI2 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBFOX2 MSI2 25348397 N/A physical interaction ComPPI
ANXA13 MSI2 25348397 N/A physical interaction ComPPI
TARDBP MSI2 25348397 N/A physical interaction ComPPI
SUZ12 MSI2 25348397 N/A physical interaction ComPPI
HNRNPA1 MSI2 25348397 N/A physical interaction ComPPI
MRPL4 MSI2 25348397 N/A physical interaction ComPPI
CRIP1 MSI2 25348397 N/A physical interaction ComPPI
LOXL3 MSI2 25348397 N/A physical interaction ComPPI
TP53 MSI2 25348397 N/A physical interaction ComPPI
UFM1 MSI2 25348397 N/A physical interaction ComPPI
G3BP1 MSI2 25348397 N/A physical interaction ComPPI
CDK1 MSI2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RHOBTB2 MSI2 25348397 N/A physical interaction ComPPI
RNF157 MSI2 25348397 N/A physical interaction ComPPI
MSI2 TIMM10B 25348397 N/A physical interaction ComPPI
MSI2 KIF21A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

Visualization