GENE:MSI2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MSI2 |
| FullNmae | musashi RNA binding protein 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:18585 |
| EnsembleID | ENSG00000153944 |
| Uniprot | Q96DH6 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MSI2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MSI2 | GO:0003723,GO:0003729,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0005844,GO:0006417,GO:0007417,GO:0008266,GO:0042802,GO:0043231,GO:0048864 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| MSI2 | hsa:124540 | path:hsa03015 | mRNA surveillance pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SUZ12 | MSI2 | 23180781 24457600 | physical association | anti tag coimmunoprecipitation | InnateDB |
| RNF2 | MSI2 | 23180781 24457600 | physical association | anti tag coimmunoprecipitation | InnateDB |
| BMI1 | MSI2 | 23180781 24457600 | physical association | anti tag coimmunoprecipitation | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | MSI2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | MSI2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | MSI2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | MSI2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HIF1A | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | MSI2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000338542 | MSI2 | N/A 20584899 | rna interference,inhibition | experimental interaction detection,western blot | miRSponge |
| URS0000338542 | MSI2 | 18668040 20584899 25416803 | mrna cleavage,inhibition | experimental interaction detection,western blot | TarBase |
| URS0000013DD8 | MSI2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00005651EE | MSI2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000292B1 | MSI2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004DA9DB | MSI2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A5E54 | MSI2 | 21572407 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000254A6 | MSI2 | 22012620 23592263 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003804D8 | MSI2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004407DC | MSI2 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000FC8EB | MSI2 | 22012620 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000019D79B | MSI2 | 22012620 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000364FEF | MSI2 | 22012620 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001799A3 | MSI2 | 22012620 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip,clip | TarBase |
| URS00003D8730 | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002233F4 | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip,clip | TarBase |
| URS000007D64A | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000031E12 | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000324096 | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A07C1 | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000B1C9 | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029979D | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237CBD | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032EF64 | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000122ED0 | MSI2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237E04 | MSI2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001B968D | MSI2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | MSI2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000235862 | MSI2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | MSI2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PIN1 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| EIF3G | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| MEOX2 | MSI2 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| FKBP1A | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| BMI1 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| ANKRD40 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPH2 | MSI2 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| GRB2 | MSI2 | 20936779 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
| UBE2L3 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| CTSB | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| CUL3 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| RAB7A | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| STIP1 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| RPA1 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| PABPC4 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| PABPC1 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| CILK1 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| RPA2 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| RPA3 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| MDM2 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| SOX2 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| RNF2 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| SF1 | MSI2 | 24234451 25348397 26420826 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
| VCAM1 | MSI2 | 19738201 24234451 25348397 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| HNRNPH1 | MSI2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| WDR1 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| H2AX | MSI2 | 20000738 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RBFOX2 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| ANXA13 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| TARDBP | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| SUZ12 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPA1 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| MRPL4 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| CRIP1 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| LOXL3 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| TP53 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| UFM1 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| G3BP1 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| CDK1 | MSI2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RHOBTB2 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| RNF157 | MSI2 | 25348397 | N/A | physical interaction | ComPPI |
| MSI2 | TIMM10B | 25348397 | N/A | physical interaction | ComPPI |
| MSI2 | KIF21A | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
