GENE:NDRG4
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | NDRG4 |
| FullNmae | NDRG family member 4 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:14466 |
| EnsembleID | ENSG00000103034 |
| Uniprot | Q9ULP0 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| NDRG4 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| NDRG4 | GO:0001947,GO:0003674,GO:0005515,GO:0005737,GO:0005737,GO:0005737,GO:0005739,GO:0005789,GO:0005829,GO:0005886,GO:0007165,GO:0008542,GO:0010642,GO:0010976,GO:0014912,GO:0016323,GO:0030154,GO:0031253,GO:0035050,GO:0048278,GO:0048662,GO:0060038,GO:0060973,GO:0070374,GO:0070374,GO:0070374,GO:2001135 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | NDRG4 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | NDRG4 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | NDRG4 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | NDRG4 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | NDRG4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | NDRG4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | NDRG4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | NDRG4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | NDRG4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | NDRG4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | NDRG4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | NDRG4 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00002D2333 | NDRG4 | 23446348 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | NDRG4 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | NDRG4 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F74F1 | NDRG4 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000136174 | NDRG4 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | NDRG4 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E1509 | NDRG4 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E628F | NDRG4 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| RABAC1 | NDRG4 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| HAX1 | NDRG4 | 25348397 | N/A | physical interaction | ComPPI |
| AGTRAP | NDRG4 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| FXYD1 | NDRG4 | 25348397 | N/A | physical interaction | ComPPI |
| NUFIP1 | NDRG4 | 25348397 | N/A | physical interaction | ComPPI |
| TP53 | NDRG4 | 25348397 | N/A | physical interaction | ComPPI |
| CMTM5 | NDRG4 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
