Gene Information gene info

GENE:NEIL1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NEIL1
FullNmae nei like DNA glycosylase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18448
EnsembleID ENSG00000140398
Uniprot Q96FI4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NEIL1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NEIL1 GO:0003684,GO:0003906,GO:0003906,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005694,GO:0005737,GO:0005815,GO:0005829,GO:0006284,GO:0006284,GO:0006287,GO:0006979,GO:0008270,GO:0016798,GO:0019104,GO:0019104,GO:0032074,GO:0045008,GO:0140078

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NEIL1 hsa:79661 path:hsa03410 Base excision repair - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 NEIL1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NEIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 NEIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 NEIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 NEIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN NEIL1 16118226 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 NEIL1 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
MAPK8 NEIL1 22135298 phosphorylation N/A PhosphoSite
XRCC1 NEIL1 25361965 interaction type N/A PTMCode2
NEIL1 XRCC1 25361965 interaction type N/A PTMCode2
NEIL1 LIG3 25361965 interaction type N/A PTMCode2
LIG3 NEIL1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
POLB NEIL1 25348397 N/A physical interaction ComPPI
XRCC1 NEIL1 14525934 15260972 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HNRNPL NEIL1 25348397 N/A physical interaction ComPPI
LIG3 NEIL1 25348397 N/A physical interaction ComPPI
NEIL1 APP 25348397 N/A physical interaction ComPPI
H3C15 NEIL1 24234451 30021884 physical association cross-linking study IntAct
WRN NEIL1 17611195 20346739 27898060 stimulant N/A OmniPath
ERCC6 NEIL1 19179336 27898060 stimulant N/A OmniPath

Visualization