GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
NEIL1 |
FullNmae |
nei like DNA glycosylase 1 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:18448 |
EnsembleID |
ENSG00000140398 |
Uniprot |
Q96FI4 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
NEIL1 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
NEIL1 |
GO:0003684,GO:0003906,GO:0003906,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005694,GO:0005737,GO:0005815,GO:0005829,GO:0006284,GO:0006284,GO:0006287,GO:0006979,GO:0008270,GO:0016798,GO:0019104,GO:0019104,GO:0032074,GO:0045008,GO:0140078 |
KEGG Annotation:
GeneSymbol |
GeneID |
Pathway |
Pathway Name |
NEIL1 |
hsa:79661 |
path:hsa03410 |
Base excision repair - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ETS1 |
NEIL1 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
NEIL1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
RUNX1 |
NEIL1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
SPI1 |
NEIL1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
ZNF263 |
NEIL1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
JUN |
NEIL1 |
16118226
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS0000237AF9 |
NEIL1 |
18185580
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
MAPK8 |
NEIL1 |
22135298
|
phosphorylation |
N/A |
PhosphoSite |
XRCC1 |
NEIL1 |
25361965
|
interaction type |
N/A |
PTMCode2 |
NEIL1 |
XRCC1 |
25361965
|
interaction type |
N/A |
PTMCode2 |
NEIL1 |
LIG3 |
25361965
|
interaction type |
N/A |
PTMCode2 |
LIG3 |
NEIL1 |
25361965
|
interaction type |
N/A |
PTMCode2 |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
POLB |
NEIL1 |
25348397
|
N/A |
physical interaction |
ComPPI |
XRCC1 |
NEIL1 |
14525934
15260972
25348397
|
N/A |
experimental interaction detection,physical interaction,in vitro |
ComPPI,HPRD |
HNRNPL |
NEIL1 |
25348397
|
N/A |
physical interaction |
ComPPI |
LIG3 |
NEIL1 |
25348397
|
N/A |
physical interaction |
ComPPI |
NEIL1 |
APP |
25348397
|
N/A |
physical interaction |
ComPPI |
H3C15 |
NEIL1 |
24234451
30021884
|
physical association |
cross-linking study |
IntAct |
WRN |
NEIL1 |
17611195
20346739
27898060
|
stimulant |
N/A |
OmniPath |
ERCC6 |
NEIL1 |
19179336
27898060
|
stimulant |
N/A |
OmniPath |
Visualization