GENE:NQO2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | NQO2 |
| FullNmae | N-ribosyldihydronicotinamide:quinone dehydrogenase 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:7856 |
| EnsembleID | ENSG00000124588 |
| Uniprot | P16083 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| NQO2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| NQO2 | GO:0001512,GO:0003955,GO:0005515,GO:0005654,GO:0005829,GO:0005829,GO:0005829,GO:0008270,GO:0009055,GO:0016491,GO:0016661,GO:0022900,GO:0031404,GO:0042803,GO:0070062,GO:0071949,GO:1901662,GO:1904408,GO:1905594 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| RHOB | NQO2 | 19637314 23180781 | physical association | two hybrid | InnateDB |
| NQO2 | JUN | 19666106 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| NQO2 | CEBPA | 23180781 24142791 | physical association | anti tag coimmunoprecipitation | InnateDB |
| YWHAZ | NQO2 | 23180781 23840115 | physical association | two hybrid | InnateDB |
| NQO2 | UBB | 23180781 24816145 | ubiquitination reaction | deubiquitinase assay | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | NQO2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | NQO2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | NQO2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | NQO2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | NQO2 | 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| JUND | NQO2 | 16545679 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
| YBX1 | NQO2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SP1 | NQO2 | 11154737 15451063 | trascriptional regulation,stimulation | inferred by curator,electrophoretic mobility shift assay | TFlink |
| SP3 | NQO2 | 15451063 | trascriptional regulation,stimulation | electrophoretic mobility shift assay | TFlink |
| TFAP2C | NQO2 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| NFE2L2 | NQO2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SMARCA4 | NQO2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | NQO2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | NQO2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | NQO2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | NQO2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | NQO2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | NQO2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | NQO2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | NQO2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | NQO2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | NQO2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| DAND5 | NQO2 | 11154737 15451063 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00003CF1AD | NQO2 | 19536157 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS000018D2BE | NQO2 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001F373E | NQO2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000411752 | NQO2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000753AD | NQO2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | NQO2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000048D44E | NQO2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CE28 | NQO2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EEF5F | NQO2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032835F | NQO2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003380CC | NQO2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00006DE17B | NQO2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000259AE4 | NQO2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000100748 | NQO2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000020CEC2 | NQO2 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000486E0B | NQO2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005F305A | NQO2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ACA7C | NQO2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171FEC | NQO2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AA464 | NQO2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000367985 | NQO2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000004CA3 | NQO2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NQO2 | GORASP2 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| NQO2 | COPS5 | 25348397 | N/A | physical interaction | ComPPI |
| NQO2 | RPS6KA2 | 25348397 | N/A | physical interaction | ComPPI |
| NQO2 | CENPF | 25348397 | N/A | physical interaction | ComPPI |
| NQO2 | DGCR6 | 25348397 | N/A | physical interaction | ComPPI |
| NQO2 | IL32 | 25348397 | N/A | physical interaction | ComPPI |
| NQO2 | LRRC7 | 25348397 | N/A | physical interaction | ComPPI |
| NQO2 | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| NQO2 | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| NQO2 | HNRNPL | 25348397 | N/A | physical interaction | ComPPI |
| NQO2 | RELB | 14743216 24234451 25348397 | physical association | tandem affinity purification | ComPPI,IntAct |
| NQO2 | RHOB | 19637314 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| NQO2 | EGFR | 24189400 24234451 25348397 | association | tandem affinity purification | ComPPI,IntAct |
| NQO2 | EFHC1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| NQO2 | DDIT4L | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| NQO2 | SPG21 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| NQO2 | HSCB | 24234451 24606901 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid | ComPPI,IntAct |
| NQO2 | NQO2 | 10433694 14525934 9050836 | N/A | experimental interaction detection | HPRD |
| NQO2 | CEBPA | 24142791 27898060 | N/A | N/A | OmniPath |
