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GENE：NUAK2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NUAK2
FullNmae NUAK family kinase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29558
EnsembleID ENSG00000163545
Uniprot Q9H093

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NUAK2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NUAK2 GO:0000287,GO:0004674,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0006468,GO:0006468,GO:0006915,GO:0030036,GO:0031588,GO:0032007,GO:0034504,GO:0035330,GO:0035556,GO:0042149,GO:0042149,GO:0043066,GO:0106310

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP NUAK2 21832049 23180781 physical association protein array InnateDB
NUAK2 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR NUAK2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NUAK2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 NUAK2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 NUAK2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 NUAK2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NUAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NUAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NUAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NUAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NUAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NUAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NUAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NUAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NUAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 NUAK2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000308E4D NUAK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004AC389 NUAK2 25074381 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000075BDA4 NUAK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004D84DB NUAK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 NUAK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC NUAK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000A9FB9 NUAK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004214BB NUAK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001FA076 NUAK2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C36BD NUAK2 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
STK11 NUAK2 22135298 phosphorylation N/A PhosphoSite
NUAK2 LATS1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SMAD4 NUAK2 25348397 N/A in vivo ComPPI
HSP90AB1 NUAK2 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SMAD2 NUAK2 25348397 N/A in vivo ComPPI
USP7 NUAK2 25348397 N/A physical interaction ComPPI
FLNC NUAK2 25348397 N/A physical interaction ComPPI
PPP1R12A NUAK2 25348397 N/A physical interaction ComPPI
PRKAA1 NUAK2 25348397 N/A physical interaction ComPPI
HSP90AA1 NUAK2 16306228 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
BTRC NUAK2 25348397 N/A physical interaction ComPPI
MARK2 NUAK2 25348397 N/A physical interaction ComPPI
GRIPAP1 NUAK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDC37 NUAK2 16306228 24234451 25348397 association tandem affinity purification ComPPI,IntAct
MARK3 NUAK2 25348397 N/A physical interaction ComPPI
ACVR1 NUAK2 25348397 N/A in vivo ComPPI
ELAVL1 NUAK2 25348397 N/A physical interaction ComPPI
LATS1 NUAK2 25348397 N/A physical interaction ComPPI
FBXW11 NUAK2 25348397 N/A physical interaction ComPPI
NUAK2 APP 25348397 N/A physical interaction ComPPI
NUAK2 HSP90AA2P 25348397 N/A physical interaction ComPPI
NUAK2 UBXN7 25348397 N/A physical interaction ComPPI
NUAK2 AHCYL2 25348397 N/A physical interaction ComPPI
NUAK2 DCAF5 25348397 N/A physical interaction ComPPI
LZTR1 NUAK2 25348397 N/A physical interaction ComPPI
STK11 NUAK2 14976552 27898060 stimulant N/A OmniPath
NUAK2 LATS1 18669648 18691976 19369195 19413330 19690332 19927127 27898060 inhibition N/A OmniPath

Visualization










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