Gene Information gene info

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GENE：OSMR

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol OSMR
FullNmae oncostatin M receptor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8507
EnsembleID ENSG00000145623
Uniprot Q99650

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
OSMR immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
OSMR GO:0002675,GO:0004896,GO:0004924,GO:0004924,GO:0005127,GO:0005515,GO:0005886,GO:0005900,GO:0008284,GO:0008284,GO:0009897,GO:0016324,GO:0019221,GO:0019838,GO:0019955,GO:0034097,GO:0038165,GO:0043235

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
OSMR hsa:9180 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
OSMR hsa:9180 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
OSMR hsa:9180 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
OSMR IL6ST 10692570 18988627 21071413 23331499 8999038 9188471 stimulation N/A SignaLink,SignaLink
IL31 OSMR 16286453 23331499 stimulation N/A SignaLink,SignaLink
OSM OSMR 16286453 23331499 stimulation N/A SignaLink,SignaLink
OSMR JAK2 10586060 23331499 stimulation N/A SignaLink
OSMR JAK1 10586060 15935618 23331499 stimulation N/A SignaLink
OSMR STAT3 10582086 23331499 stimulation N/A SignaLink
OSMR STAT1 10582086 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR OSMR 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA OSMR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF OSMR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 OSMR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 OSMR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS OSMR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 OSMR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A OSMR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 OSMR 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 OSMR 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 OSMR 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000061E50F OSMR 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB16 OSMR 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000605E00 OSMR 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001A405B OSMR 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC OSMR 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000014F13C OSMR 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000279B6F OSMR 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 OSMR 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001B12A4 OSMR 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 OSMR 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048F59D OSMR 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCDA3 OSMR 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E OSMR 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 OSMR 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 OSMR 19536157 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 OSMR 19536157 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 OSMR 19536157 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 OSMR 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 OSMR 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000AB32B OSMR 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C OSMR 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B OSMR 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 OSMR 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F OSMR 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 OSMR 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
OSMR IL6ST 25361965 interaction type N/A PTMCode2
IL6ST OSMR 25361965 interaction type N/A PTMCode2
OSMR JAK1 25361965 interaction type N/A PTMCode2
JAK1 OSMR 25361965 interaction type N/A PTMCode2
OSMR JAK2 25361965 interaction type N/A PTMCode2
JAK2 OSMR 25361965 interaction type N/A PTMCode2
OSM OSMR 25361965 interaction type N/A PTMCode2
OSMR OSM 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CUL5 OSMR 25348397 N/A physical interaction ComPPI
BAG3 OSMR 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SGTB OSMR 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ERBB2 OSMR 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
IL6ST OSMR 14525934 24234451 24501689 25348397 9188471 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
OSM OSMR 10997905 14525934 25348397 8999038 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
OSMR JAK1 10586060 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
OSMR JAK2 10586060 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
OSMR GAPDH 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
OSMR EGFR 25348397 N/A physical interaction ComPPI
OSMR ANKLE2 25348397 N/A physical interaction ComPPI
OSMR TRIM25 25348397 N/A physical interaction ComPPI
OSMR SLC10A6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
OSMR GPRC5D 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
OSMR UBQLN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
OSMR LHX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IL6ST OSMR 10854424 27898060 8999038 9188471 N/A N/A OmniPath
OSMR IL31RA 15184896 15194700 27898060 N/A N/A OmniPath
IL31 OSMR 15184896 27898060 stimulant N/A OmniPath
OSM OSMR 10854424 10997905 16286453 27898060 8999038 stimulant N/A OmniPath

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