Gene Information gene info

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GENE：PNMT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PNMT
FullNmae phenylethanolamine N-methyltransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9160
EnsembleID ENSG00000141744
Uniprot P11086

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PNMT immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PNMT GO:0004603,GO:0004603,GO:0004603,GO:0004603,GO:0005515,GO:0005829,GO:0005829,GO:0032259,GO:0042418,GO:0042423

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PNMT hsa:5409 path:hsa00350 Tyrosine metabolism - Homo sapiens (human)
PNMT hsa:5409 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA1 PNMT 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PNMT 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF PNMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PNMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 PNMT 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
TERF1 PNMT 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ESR1 PNMT 25348397 N/A physical interaction ComPPI
TERF2IP PNMT 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
LNX1 PNMT 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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