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GENE：PPBP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPBP
FullNmae pro-platelet basic protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9240
EnsembleID ENSG00000163736
Uniprot P02775

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPBP immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PPBP ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PPBP GO:0005355,GO:0005515,GO:0005576,GO:0005615,GO:0006954,GO:0008009,GO:0008083,GO:0030593,GO:0031093,GO:0042742,GO:0045236,GO:0051781,GO:0061844,GO:0070098,GO:0071222,GO:1904659,GO:1904724

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PPBP hsa:5473 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
PPBP hsa:5473 path:hsa04061 Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human)
PPBP hsa:5473 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PPBP PPBP 23180781 8195702 physical association cross-linking study InnateDB
PPBP CXCR2 23180781 8702798 9126332 physical association competition binding InnateDB
PPBP MMP9 18660381 23180781 protein cleavage protease assay InnateDB
PPBP MMP1 18660381 23180781 protein cleavage protease assay InnateDB
IL7R PPBP 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
MMP12 PPBP 18660381 23180781 protein cleavage protease assay InnateDB

Source Target Pmid Interactiontype Methods Database
AR PPBP 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SPI1 PPBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TBP PPBP 7958954 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 PPBP 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
CXCR1 PPBP 25361965 interaction type N/A PTMCode2
PPBP CXCR1 25361965 interaction type N/A PTMCode2
ALB PPBP 25361965 interaction type N/A PTMCode2
PPBP ALB 25361965 interaction type N/A PTMCode2
CTSG PPBP 25361965 interaction type N/A PTMCode2
PPBP CTSG 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CXCL9 PPBP 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CTSG PPBP 1387511 14525934 1873479 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RAB10 PPBP 25348397 N/A physical interaction ComPPI
COX17 PPBP 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CCL5 PPBP 24234451 25348397 28381538 N/A filter binding,surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
EFNA1 PPBP 14525934 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MAPK6 PPBP 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CXCR2 PPBP 14525934 25348397 8195702 8702798 N/A experimental interaction detection,physical interaction,biochemical,in vivo ComPPI,HPRD
CCL13 PPBP 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CCL8 PPBP 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CXCL12 PPBP 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
NR4A1 PPBP 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
COPS7A PPBP 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CXCL11 PPBP 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
PMAIP1 PPBP 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CCL28 PPBP 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CCL21 PPBP 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
COPG1 PPBP 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
STRN4 PPBP 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CCL26 PPBP 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
SCFD1 PPBP 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PPBP CELF1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PPBP DMWD 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PPBP CXCR1 1427896 14525934 25348397 8195702 N/A experimental interaction detection,physical interaction,biochemical,in vitro,in vivo ComPPI,HPRD
PPBP CMTM6 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPBP RPS27 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPBP MOB3B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPBP PLEKHJ1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPBP NDUFB11 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPBP ALB 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PPBP QRSL1 21900206 24234451 25348397 physical association two hybrid ComPPI,IntAct
PPBP CXCL6 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
PPBP CXCL10 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CXCL14 PPBP 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
PPBP PPBP 14525934 7706245 N/A experimental interaction detection HPRD
IL7R PPBP 20167604 27898060 N/A N/A OmniPath
MMP9 PPBP 18660381 27898060 N/A N/A OmniPath
MMP1 PPBP 18660381 27898060 N/A N/A OmniPath
PPBP CXCR2 24218476 27898060 8195702 8550564 8702798 9126332 stimulant N/A OmniPath
PPBP CXCR1 1427896 24218476 27898060 8195702 8702798 stimulant N/A OmniPath

Visualization










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